Protein Info for Pf6N2E2_2436 in Pseudomonas fluorescens FW300-N2E2

Annotation: DNA-binding response regulator, LuxR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 PF00072: Response_reg" amino acids 4 to 115 (112 residues), 96.1 bits, see alignment E=1.5e-31 PF00196: GerE" amino acids 150 to 202 (53 residues), 72 bits, see alignment E=2.4e-24

Best Hits

Swiss-Prot: 57% identical to BVGA_BORPE: Virulence factors putative positive transcription regulator BvgA (bvgA) from Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)

KEGG orthology group: K07690, two-component system, NarL family, response regulator EvgA (inferred from 100% identity to pba:PSEBR_a1638)

Predicted SEED Role

"DNA-binding response regulator, LuxR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZVR9 at UniProt or InterPro

Protein Sequence (208 amino acids)

>Pf6N2E2_2436 DNA-binding response regulator, LuxR family (Pseudomonas fluorescens FW300-N2E2)
MNSVFIVDDHPVIRLAVRMLLEHEGYKVVGETDNGVDAMQMVRECMPDLVILDISIPKLD
GLEILSRFNAMTTPLKTLVLTAQSPTLFGIRCMQSGASGYVCKQEDLSELVSAIKAVLSG
YNYFPSQALNPVRPDDPRSIELDLFKSVNDRELMVLQLFAQGRTNKEIAKGMFLSNKTVS
TYKKRLMQKLKVKSLVDLIEMAKRNALV