Protein Info for Pf6N2E2_2403 in Pseudomonas fluorescens FW300-N2E2

Annotation: Pyoverdine chromophore precursor synthetase PvdL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 500 1000 1500 2000 2500 3000 3500 4000 4328 transmembrane" amino acids 77 to 95 (19 residues), see Phobius details amino acids 219 to 242 (24 residues), see Phobius details amino acids 1969 to 1987 (19 residues), see Phobius details amino acids 2246 to 2265 (20 residues), see Phobius details PF00501: AMP-binding" amino acids 15 to 407 (393 residues), 237.5 bits, see alignment E=4.7e-74 amino acids 1132 to 1478 (347 residues), 313.9 bits, see alignment E=2.7e-97 amino acids 2191 to 2544 (354 residues), 276.5 bits, see alignment E=6.5e-86 amino acids 3720 to 4074 (355 residues), 243.6 bits, see alignment E=6.5e-76 PF00550: PP-binding" amino acids 585 to 647 (63 residues), 52.8 bits, see alignment (E = 7.9e-18) amino acids 1638 to 1700 (63 residues), 49 bits, see alignment (E = 1.2e-16) amino acids 2709 to 2770 (62 residues), 57.7 bits, see alignment (E = 2.4e-19) amino acids 4238 to 4302 (65 residues), 61.4 bits, see alignment (E = 1.6e-20) PF00668: Condensation" amino acids 670 to 1111 (442 residues), 368.5 bits, see alignment E=9.4e-114 amino acids 1725 to 2171 (447 residues), 349.6 bits, see alignment E=5.2e-108 amino acids 2786 to 3228 (443 residues), 258.2 bits, see alignment E=2.8e-80 amino acids 3249 to 3699 (451 residues), 305 bits, see alignment E=1.8e-94 TIGR01733: amino acid adenylation domain" amino acids 1153 to 1552 (400 residues), 445.7 bits, see alignment E=4.3e-137 amino acids 2212 to 2618 (407 residues), 414.8 bits, see alignment E=1e-127 amino acids 3741 to 4149 (409 residues), 401.1 bits, see alignment E=1.5e-123 PF13193: AMP-binding_C" amino acids 1536 to 1613 (78 residues), 29.4 bits, see alignment (E = 2.6e-10) amino acids 2602 to 2682 (81 residues), 42.1 bits, see alignment (E = 2.8e-14) amino acids 4133 to 4210 (78 residues), 30.3 bits, see alignment (E = 1.3e-10) TIGR01720: non-ribosomal peptide synthase domain TIGR01720" amino acids 3088 to 3241 (154 residues), 143.7 bits, see alignment (E = 1.3e-45)

Best Hits

Predicted SEED Role

"Pyoverdine chromophore precursor synthetase PvdL" in subsystem Siderophore Pyoverdine

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZVP3 at UniProt or InterPro

Protein Sequence (4328 amino acids)

>Pf6N2E2_2403 Pyoverdine chromophore precursor synthetase PvdL (Pseudomonas fluorescens FW300-N2E2)
MTDAFELPSTLAHALQRRAALTPDRVALRFLADTPGQGVVLSYRDLDLRARTIAAALQAE
AALGDRAVLLFPSGPDYVAAFFGCLYAGVIAVPAYPPESTRRHHQERLLSIIADAEPRLL
LTRSDLREPLQAIESAPPVLCVDTLDPSRAGQWRMPTLQDDDIAFLQYTSGSTALPKGVQ
VSHGNLVANELLIRHGFGIDLNPDDVIVSWLPLYHDMGLIGGLLQPVFSGVPCVLMSPAY
FLARPLRWLEAISEYGGTISGGPDFAYRLCSERVSDSALQRLDLSGWRVAYSGSEPIRLD
TLERFAEKFAPCGFTPDNFMASYGLAEATLFVAGTPRRHGIPSLRVDDAALAQNRAEPGQ
GSAVMSCGVSQPGHAVLIVEPATAQPLADNQVGEVWAAGPSIALGYWRNPEASAKTFVQH
DGRTWLRTGDLGFLRDGELFITGRLKDLLIVRGHNLYPQDIEQAIEREVEVVRKGRVAAF
AVNDGGEEGIGIAAEISRSVQKILPPEALIKAIRQAVAEACQQAPSVVALLNPGALPKTS
SGKLQRSACRSRLADGSLDSYAQFPSAEVEDADESAPSSELQTLIGQIWREQLQVEQVQA
DDHFFLLGGNSIAATQMIARLREILGLELNLRLLFEAPTLAAFAEAVANQQQDGGQPQGA
ISALSRDEALPQSLAQNRLWITWRLDPTSHAYNIPGALHLRGELDEDALRTSFQQLIERH
ESLRTRFLERDGVALQQIDPAGEFKLHVIDLGDLPADSREARARQVREDEAATPFDLEKG
PLLRVTLLRLDEDDHQLLVTLHHIIADGWSMSVLIEEFSRLYAAASQGQVAELAPLPLQY
ADYGSWQRQWLAQGEAERQLSYWKQQLGAEQSALVLGTDHPRSAQRQRSAARHSLRLDKD
LGEALRHVAQAHDATPFMLLLAAFQALLQRYTGQSDIRIGVPNANRPRLETQGLIGFFIN
TQVLRGQVDSRQPFAALLAQAREATLGAQAHQDLPFEQLLEAIPEAREQGLFQVMFNHQQ
RDLSALRRLPGLLAEELPWHSREAKFDLQLHSEEDRNGRLTLSFDYADELFEAATIERLA
THYGNLLRAVCAGPQQAIGDVPLLTADEHSQQQQWSAAPCAPASQWLPELLNEQARNTPQ
RIALRWDGGQLDYAELHAQANRLAHYLRDKGVGPDVCVAIAAERSPQLLIGVLAIIKAGG
AYVPLDADYPAERLAYMLDDSGVDLLLTQTALLERLPACDGVSVIAMDALHLEQWPSNPP
GLHLHGDHLAYVIYTSGSTGQPKGVGNTHAALAERLQWMQATYGLDAIDVLMQKAPISFD
VSVWECFWPLITGSQLVLAGPGEHRDPHRIAQLVQQFGVTTLHFVPPLLSLFVDEPLSAR
CTSLRRLFSGGEALPAELRNRVLAQLPSVQLHNRYGPTETAINVTHWHCTEADGERSPIG
RPLGNVLCRVLDSDLNPVPAGVPGELCIGGLGLARGYLGRPGLSAERFVADPLGQAGARL
YRTGDRARWNADGVIEYLGRLDQQVKLRGFRVEPQEIEARLLAQDGVAQVAVLVRNTSAG
PQLIGYYTAPEVAQGQDELNTRLKAALAAELPDYMVPAQLLRLDVMPLSPSGKLDRRALP
EPQWQVREHVEPASVLEQQIAGIWRQVLGLARIGLRDDFFALGGHSLLATQIISRTRQTC
DVELPLRTLFEASELGAFAEQVRLIQASGQANRQPPIEKVDRSQPVPLSYSQQRMWFLWQ
MEPDSPAYNVGGMARLRGVLDVGRFEAALQALILRHETLRTTFPSVDGVAHQQVHGETGL
RMDWKDFSMLAFDVREQRVQQLADSEAHKPFDLETGPLLRACLVKTAEHEHYFVLTLHHI
VTEGWAMDIFARELSALYEAFIDDRESPLEPLPVQYLDYSVWQRQWLESGERQRQLDYWT
TQLGREHPLLELPGDRPRPSVQSHRGELFRFDLSDDLAARVRAFNAQQGLTLFMTMTAAL
AVLLYRYSGQTDLRIGAPVANRIRPESEGLIGAFLNTQVLRCQLDGQMSVGELFEQVRHT
VIEGQSHQDLPFDHLVEALQPPRSAAYNPLFQVMCNVQRWEFQQSRTLAGMTVEYLVNDA
RATKFDLNLEVTDLDQRLGCCLTYSTDLFDEPRIARMAGHWRNLLEALLDDPARRLSELP
LLDTREQQQLLDSLGVEPGEHHLDRCLHELFDEQARMRPDAPALTFAGQTLTYAQLDSSA
NRLAWMLRERGVGPQVRVGLALERSLEMVIGLLAILKAGGAYVPLDPEYPLDRLHYMIED
SGISLLLSDRAMLQALGALPDGVGCWCLEDDSPALAQYPDHALPLINLPQHQAYLIYTSG
STGKPKGVVVSHGEIAMHCQAVIQRFGMRPDDCELHFYSINFDAATERLLVPLLSGAHVV
LRAQGQWDAEEICGLIRQHRINILGFTPSYGSQLAQWLATQGQTLPVRMCITGGEALTGE
HLQRIRAAFNPSLFFNAYGPTETVVMPLASLAPEQLEEGAASVPIGSVIGARMAYILDAD
LALVPPGATGELYVGGAGLAQGYHQRPGMTAERFVADPFATDGGRLYRTGDLVRQRADGL
VEYLGRIDHQVKIRGFRIELGEIETRLLEHDAVREAVVLALDTPGGKQLAGYLVSDVASQ
DDGRQAALRDALKNHLKAQLPDYMVPTHLILLASMPLTANGKLDRRALPMPDPELNRQHY
VAPSNALEQTLAAIWCDVLNVTQVGLNDNFFELGGDSILSIQVVSRARQQGIHFTPRDLF
QHQTVQTLAAVATRSQQVLAEQGLLQGESGLTPIQHWFFERPIPNRHHWNQALVLEPTTA
LAPQPLEQALRSLLQHHDALRLGFDESTGHWQAEHQPLSDAALLRHVSVDTAQDCEALFA
ETQSRFNLATGPLLRAVLAQFPDGQQRLLIVIHHLVVDGVSWRVLMDDLQTVYRPLAIGQ
AAQLSAKTSPMRDWAARLQAYAGSESLREELAWWQAQLSGAQVPLPCANPEGGLLERHAE
TVSVRLDAERTRQLLQQAPSAYRTQVNDLLLTALARVLCRWSGHASTLVQLEGHGREALF
DDIDLTRTVGWFTSVYPVRLSPATEGFGASIKAIKEQLRAVPHKGLGHGVLRYLADAATR
QTMANLPHAAITFNYLGQLDQTLGHDALFQPLDAPLGAIHDPDAPLPNELSVDSQVSGGE
LLLRWTFSRERHDRQAIATLAGAYLDELQRLIEHCLTDEAGGLTPSDFPLAKLTQGQLDS
LPVPAGQIEDVYPLTPMQEGMLLHTLLEPGTGLYYMQDRYRINSELDPQRFAQAWQAVIA
RHEALRASFCWNVGEDMLQIIHRPGSTPVDYLDWSEVPEDAQEAKLQALLKNEREAGFDL
LNQAPFHLRLIRVGAARYWFMMSNHHILIDAWCRSLLMDDFFEIYTALGENREPQLTVPP
RYRDYIGWLQHQSLAEARQWWQRNLQGFERTTPIPGDRPFLREHAGDSGGMIVGDCYTRL
DARDGARLRELAQAHQLTVNTFAQAAWALVLRRVSGDRDVLFGVTVAGRPVELPQMQRTV
GLFINSIALRVQMPEDHQRCSVRQWLSDLLDHNMQLREYEYLPLVSIQEASELPKGQPLF
DSLFVFENAPVEVSVLDRAQSLNATSDSGRTHTNFPLTAVCYPGDDLGLHLSYDQRYFDE
ATVQGLLSEFKRLLLALMEGLHGDMSELPLIGAQEQDFLIEGCNQSEHAYPLEQSYVELF
EARVAAHPHRPAVSCLDTSYSYAELNARSNRLGHALIAAGVGLDQPVALLAERDAELLGM
IVGSFKAGAGYLPLDPGLPSQRLGRIIELSRTPLLVCTQACQAQAQALLDEFACSGRPKL
LVWEAVQASALSLENPGVYSGPDNLAYVIYTSGSTGLPKGVMVEQRGMLNNQLSKVPYLA
LSEVDVIAQTASQSFDISVWQFLAAPLFGARVDIVPNAIAHDPQGLLEHVQQQGITVLES
VPSLIQGMLAQERIGLDGLRWMLPTGEAMPPELAHQWLLRYPDIGLVNAYGPAECSDDVA
FFRVDLASTRGTYLPIGTPTDNNRLYLLDGALDLVPLGAVGELCVAGIGVGRGYVSDPLR
TAPVFVPNPFGAPGERLYRTGDLARRRSDGVLEYVGRIDHQVKIRGYRIELGEIEARLHE
QPEVRDGAVGVQEGVNGKHLVGYLVATDSALKPAERLERIKQRLRAELPEYMVPLHWLWL
ERLPLNANGKLDRKALPALEIGQLQSQDYQAPGNELEQTLADIWAQVLKVERVGVRDNFF
ELGGHSLLATQIASRVQKALQRNVPLRAMFECSTVQELADYIDGLAASEITEEKVDRLND
LMAELEGM