Protein Info for Pf6N2E2_2377 in Pseudomonas fluorescens FW300-N2E2

Annotation: Serine/threonine protein kinase (EC 2.7.11.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 557 transmembrane" amino acids 534 to 555 (22 residues), see Phobius details PF13672: PP2C_2" amino acids 13 to 183 (171 residues), 34.5 bits, see alignment E=3.2e-12 PF00069: Pkinase" amino acids 262 to 460 (199 residues), 101.5 bits, see alignment E=1.1e-32 PF07714: PK_Tyr_Ser-Thr" amino acids 280 to 501 (222 residues), 54.9 bits, see alignment E=1.6e-18

Best Hits

KEGG orthology group: None (inferred from 97% identity to pba:PSEBR_a1689)

Predicted SEED Role

"Serine/threonine protein kinase (EC 2.7.11.1)" (EC 2.7.11.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.11.1

Use Curated BLAST to search for 2.7.11.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZX15 at UniProt or InterPro

Protein Sequence (557 amino acids)

>Pf6N2E2_2377 Serine/threonine protein kinase (EC 2.7.11.1) (Pseudomonas fluorescens FW300-N2E2)
MSLQLSFAEASAIGPREENQDALRLVTPAPALAASKGYLFAIADGVSQCADGGLAARSTL
QALALDYYSTPQTWGVAQALDRLLLAQNRWLQANGGGQPLLTTVSVLVLRGRRFTLAHVG
DCRVYRWHADQLQRVSEDHVWEQQGMQHVLKRALGLDQHLILDFLDGELRIDETFVLLSD
GVWAVLGDTAIAGILRDQPDLDVAAQTLVNAAHLAGSQDNASALLVRVDAVGEASIGDAL
IQLQQWPLPPALKPGQVFEGWQIESLLGQSQQSLLYRVHDGQGQPWLLKTLPAQLRDDSR
AGQALLSEEWFLKRVAGRQFPEVHGVPQRQHLYYVMREYPGATLAELFNQGGPLPLAQWL
ELAQRLVRAVGLLHRRQIYHRDIKPENLHLGDDGELRLLDFGLAYCPGLSEDQANVLPGT
PSYIAPEAFAGTAPTAQQDLYSVGVTLYFLLTGHYPYGEIEAFQRPRFGVPVSASRYRPD
LAEWLGQSLERAVAADPEQRFETAEEWLLLLEQGERRSLNVRPRPLLEREPLKVWRTLAL
VSLVVNIVLLFLVFHGS