Protein Info for Pf6N2E2_2293 in Pseudomonas fluorescens FW300-N2E2

Annotation: COG0488: ATPase components of ABC transporters with duplicated ATPase domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 636 PF00005: ABC_tran" amino acids 19 to 182 (164 residues), 80.9 bits, see alignment E=2.9e-26 amino acids 334 to 467 (134 residues), 74.8 bits, see alignment E=2.3e-24 PF12848: ABC_tran_Xtn" amino acids 221 to 297 (77 residues), 33.3 bits, see alignment E=8.2e-12 PF16326: ABC_tran_CTD" amino acids 567 to 635 (69 residues), 74 bits, see alignment E=1.8e-24

Best Hits

Swiss-Prot: 54% identical to UUP1_HAEIN: ABC transporter ATP-binding protein uup-1 (uup-A) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a1744)

Predicted SEED Role

"COG0488: ATPase components of ABC transporters with duplicated ATPase domains" in subsystem Folate Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZY32 at UniProt or InterPro

Protein Sequence (636 amino acids)

>Pf6N2E2_2293 COG0488: ATPase components of ABC transporters with duplicated ATPase domains (Pseudomonas fluorescens FW300-N2E2)
MTLLKFSDVSLAFGAMPLLDKVSWQIARGERVCIIGRNGTGKSSMMKLVKGDQKPDDGSV
WRAPGLKIGELPQELPVADERTVFDVVAEGLDGVGALLAEYHHLSQNIVTDADLDKLMHV
QHDLEARDGWRLQQLVDSTLSRLQLPADKTLAELSGGWRRRVLLAQALVSEPDLLLLDEP
TNHLDIGAIAWLEEALKDFQGAVLFITHDRSFLQNLATRILELDRGGLIDWNGDYASFLV
HKEAALAAEETANALFDKKLAQEEVWIRQGIKARRTRNEGRVRALKALRVERSERRERTG
KANIQLDTADKSGKQVMVLENVSFAHPGGPFLIKDFSMVLQRGDRIGLLGANGTGKTTLL
KLMLGGLVPTNGKVEEGTKIDVAYFDQLRHQLDLEKTVIDNVAEGRDFIDIDGQSRHVLS
YLGDFLFSPQRARTPVKALSGGERARLLLAKLFSKPANLLVLDEPTNDLDVETLELLEEV
LLTFNGTVLMVSHDRAFLDNVVTSTLVFEGEGLVREYVGGYQDWLRQGGSPRLLGVTESK
SGKADLNSAVVKAEPAPVAAAAPAKKKLSYKLQRELEALPGDIDAKEQQIAAVEAEMADA
GFYQRPAAETAKVIAHLEQLQAELDALVERWAELDA