Protein Info for Pf6N2E2_1967 in Pseudomonas fluorescens FW300-N2E2

Annotation: Cobalt-zinc-cadmium resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 209 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 59 to 81 (23 residues), see Phobius details amino acids 87 to 108 (22 residues), see Phobius details PF01545: Cation_efflux" amino acids 6 to 117 (112 residues), 52.2 bits, see alignment E=3.5e-18

Best Hits

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (209 amino acids)

>Pf6N2E2_1967 Cobalt-zinc-cadmium resistance protein (Pseudomonas fluorescens FW300-N2E2)
MPSSNGVSGIITGGREIELGMVIIYAAVFTVVEFGYFFYVRYRNRTLKSSLIQFDNISWL
VDAMLSVGLLVSFLIALLLKAQGYGQWAMYVDPLILILLALSMLAPAFKILRPALRDVLG
IAPDQLDDTVRQVMDAATVEHGFEDYVSYVQKHGRARFIEIHIVLPADYRLQTVGQLDAI
REQISARLGQADATRWLTICFTGDRKWIA