Protein Info for Pf6N2E2_1889 in Pseudomonas fluorescens FW300-N2E2

Annotation: Permease of the drug/metabolite transporter (DMT) superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 272 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 28 to 48 (21 residues), see Phobius details amino acids 59 to 77 (19 residues), see Phobius details amino acids 83 to 102 (20 residues), see Phobius details amino acids 109 to 130 (22 residues), see Phobius details amino acids 136 to 154 (19 residues), see Phobius details amino acids 166 to 185 (20 residues), see Phobius details amino acids 194 to 215 (22 residues), see Phobius details amino acids 224 to 244 (21 residues), see Phobius details amino acids 250 to 268 (19 residues), see Phobius details PF00892: EamA" amino acids 139 to 266 (128 residues), 55.2 bits, see alignment E=4.2e-19

Best Hits

Swiss-Prot: 58% identical to Y1977_PSEAE: Uncharacterized protein PA1977 (PA1977) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 60% identity to pst:PSPTO_4266)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161GMM6 at UniProt or InterPro

Protein Sequence (272 amino acids)

>Pf6N2E2_1889 Permease of the drug/metabolite transporter (DMT) superfamily (Pseudomonas fluorescens FW300-N2E2)
MTCFAMLAFAANSLLCRLALKHTAIDAASFSVVRLASGALVLWLMCALRRSSNTIKGSWK
GAAALFVYVFAFSFAYRHLETGTGALLLFGAVQLSMVLYGLFKGERMHALAIVGFVLAIV
GLVSLLLPGAAAPDPVSAFTMLLSGVAWGIYSLLGKTVADPLATTTGNFLRSIPLVLIAS
LPFLSELRWDPQGILYAVLSGALASGFGYAVWYVAVCHLAAFQAATVQLSVPILASLAGI
VFLGEALSERIVLASVAVLGGVALVLGGKPRA