Protein Info for Pf6N2E2_1880 in Pseudomonas fluorescens FW300-N2E2

Annotation: Putative protein-S-isoprenylcysteine methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 157 transmembrane" amino acids 15 to 32 (18 residues), see Phobius details amino acids 43 to 66 (24 residues), see Phobius details amino acids 99 to 126 (28 residues), see Phobius details PF04191: PEMT" amino acids 45 to 144 (100 residues), 54.9 bits, see alignment E=1.1e-18 PF04140: ICMT" amino acids 75 to 139 (65 residues), 28 bits, see alignment E=2.3e-10

Best Hits

KEGG orthology group: None (inferred from 94% identity to smk:Sinme_6873)

Predicted SEED Role

"Putative protein-S-isoprenylcysteine methyltransferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165Z4G8 at UniProt or InterPro

Protein Sequence (157 amino acids)

>Pf6N2E2_1880 Putative protein-S-isoprenylcysteine methyltransferase (Pseudomonas fluorescens FW300-N2E2)
MSVEPHNAGVRFPPPLLYLGALLLGLAADRFITLRSFGIDWRLLVATGALLFVAGAAMML
AAAGLFRRLGTNIPPSQPTTLIATTGPYRWTRNPMYLGMALIYAGLAIGFDGPIAFALLP
LVLIAIQRQVIAREERYLEAKFGDDYRRYKAKVRRWL