Protein Info for Pf6N2E2_182 in Pseudomonas fluorescens FW300-N2E2

Annotation: Two-component hybrid sensor and regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1130 transmembrane" amino acids 45 to 69 (25 residues), see Phobius details amino acids 75 to 97 (23 residues), see Phobius details amino acids 112 to 140 (29 residues), see Phobius details amino acids 147 to 170 (24 residues), see Phobius details amino acids 181 to 198 (18 residues), see Phobius details amino acids 218 to 238 (21 residues), see Phobius details amino acids 258 to 287 (30 residues), see Phobius details amino acids 305 to 328 (24 residues), see Phobius details amino acids 360 to 381 (22 residues), see Phobius details amino acids 388 to 406 (19 residues), see Phobius details amino acids 427 to 450 (24 residues), see Phobius details amino acids 457 to 477 (21 residues), see Phobius details amino acids 571 to 592 (22 residues), see Phobius details amino acids 612 to 632 (21 residues), see Phobius details PF00512: HisKA" amino acids 679 to 745 (67 residues), 65.9 bits, see alignment 4.2e-22 PF02518: HATPase_c" amino acids 792 to 899 (108 residues), 95.2 bits, see alignment E=5.3e-31 PF00072: Response_reg" amino acids 925 to 1036 (112 residues), 87.9 bits, see alignment E=8.1e-29

Best Hits

Predicted SEED Role

"Two-component hybrid sensor and regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165YM79 at UniProt or InterPro

Protein Sequence (1130 amino acids)

>Pf6N2E2_182 Two-component hybrid sensor and regulator (Pseudomonas fluorescens FW300-N2E2)
VLPPGTQRIAKIRRDYNSWVADETMEDYALRYTPKSFRRWSELRIANTALGAVSFLALEA
IGGVLALSYGFTNTFWAILAVSLIIFLTGLPVSYYAARYGVDMDLLTRGAGFGYIGSTIT
SLIYASFTFLFFALEAAIMALALELYFHIPLAFAYVICSVLVIPLVAYGVTLISRLQLWT
QPLWLVLLVLPYLFVLLKNPEAFSDWTSFQGRDASGDFNLLAFCAACTVALSLVTQIGEQ
VDYLRFLPEKTAANRKRWWAALLCAGPGWILPGALKMFAGAFLAFLALQHEIPIERATEP
TQMYLVAFGYVFASPEWALAAMVLFVFVSQMKINLTNAYAGSLAWSNFFARVTHSHPGRV
VWLVFNVAIALMLMELGVFDVIDQVLGLYANIAIAWIGSVVADLVINKPLGLSPKYIEFK
RAHLYDINPVGVGSMLIASLLSVLAHFGLFGALAQAAPPFVALGTSLVMTPLLAWATRSR
YYIARTRDPLLLQPVAPSTLITCGLCSNPFETADMAFCPAYSTPICSLCCSLDARCGDRC
KPHGRLSAQFEALLHWLLPNATVPRLHTRLVHYLGLLLALILMLSGALALIYGQASQGLP
HSPQAQATLYQAFFQAFLTLSVLAAILAWWVVLTRESRRVAQEESDRQTLLLMQEIEAHR
LTDQALQDAKEASEAANAAKSRYVTGLSHELRTPLNSILGFTQILQRDAAMPEQHQDALA
TILRSGSHLLSLIDGLLDVAKIEAGKLRLEPTEIPFPELIHDLELMFTPQARDKGLRFRL
ELIGKMPAVVRGDEKRVRQILINLLGNAVNFTDSGEVCLRVSYMRETATFDIIDTGIGID
PEHIERIFQPFERGDLMRQDKGVGLGLTITRMLTSLMGGELQVKSQQDKGTCFQVRLFLS
QVRVPQAVIHVEHDIIGYQGPRRLVLVVDDHVDHRKVLSGMLTPLGFEVVQASNGQEAIR
QVALLGPDLILMDLSMPTMDGWETSRLIRRNALSTAPIIVISANAFNDERERSLASVCND
YLAKPVHTPELLERIQKQLDLHWLRREKPAPATFPEPGILPSQPDLIALGELSAIGYVRG
LHEKLDAIQAETPATAPFISSLRKLLKNFRLDEINRALKEAEDECTDHSR