Protein Info for Pf6N2E2_1778 in Pseudomonas fluorescens FW300-N2E2

Annotation: Positive regulator of CheA protein activity (CheW)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 174 PF01584: CheW" amino acids 17 to 157 (141 residues), 121.7 bits, see alignment E=8.7e-40

Best Hits

Swiss-Prot: 39% identical to CHEW_ECO57: Chemotaxis protein CheW (cheW) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 96% identity to pba:PSEBR_a2250)

Predicted SEED Role

"Positive regulator of CheA protein activity (CheW)" in subsystem Bacterial Chemotaxis or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZWC2 at UniProt or InterPro

Protein Sequence (174 amino acids)

>Pf6N2E2_1778 Positive regulator of CheA protein activity (CheW) (Pseudomonas fluorescens FW300-N2E2)
MSISASRLPAPGTAAPQYLTFSVGQEMFAVGTLCVREIVEYGPITPLPMAPAKVRGITNL
RGAAIPVLDLGLCFGGVQTLENPRTCIVMLEVHGSGGAGLVGIIVDAVSEVLEIPAEQIE
PAPALQGRLSPAFVVGIGKLSDRFVLLLDIEHMLSSEDWSALLPSNINADGLRP