Protein Info for Pf6N2E2_1606 in Pseudomonas fluorescens FW300-N2E2
Annotation: Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 66% identical to NSPC_HERAR: Carboxynorspermidine/carboxyspermidine decarboxylase (nspC) from Herminiimonas arsenicoxydans
KEGG orthology group: K13747, carboxynorspermidine decarboxylase [EC: 4.1.1.-] (inferred from 100% identity to pba:PSEBR_a2444)MetaCyc: 50% identical to carboxynorspermidine decarboxylase (Vibrio cholerae)
RXN-9380 [EC: 4.1.1.96]
Predicted SEED Role
"Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-)" in subsystem Polyamine Metabolism (EC 4.1.1.-)
MetaCyc Pathways
- norspermidine biosynthesis (4/6 steps found)
- spermidine biosynthesis II (2/4 steps found)
- superpathway of polyamine biosynthesis III (4/8 steps found)
KEGG Metabolic Maps
- 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
- 1- and 2-Methylnaphthalene degradation
- 3-Chloroacrylic acid degradation
- Ascorbate and aldarate metabolism
- Benzoate degradation via hydroxylation
- Biphenyl degradation
- Fluorene degradation
- Phenylalanine metabolism
- Phenylpropanoid biosynthesis
- Purine metabolism
- Pyruvate metabolism
- Tryptophan metabolism
- Tyrosine metabolism
- Ubiquinone and menaquinone biosynthesis
Isozymes
Compare fitness of predicted isozymes for: 4.1.1.-
Use Curated BLAST to search for 4.1.1.- or 4.1.1.96
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0N9X3W3 at UniProt or InterPro
Protein Sequence (365 amino acids)
>Pf6N2E2_1606 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) (Pseudomonas fluorescens FW300-N2E2) MIKTPYYLIDKQKLLANMQKIAYVREQSGAKALLALKCFATWSVFDLMQQYMDGTTSSSL YELKLGRQKFAGETHAYSVAWADDEIEEMLANCDKIIFNSIGQLQRYTEASAGKVRGLRV NPQVSSSDYLLADPARPFSRLGEWDPVKIEQVIEHISGFMFHNNCENGDFGLFDQMLGTI EERFGHLLHKVEWVSLGGGIHFTGEGYALDAFCARLKAFSQKYGVQVYLEPGEAAITQSA SLEVTVLDTLYNGKHLAVVDSSIEAHMLDLLIYRLDAKLAPSEGEHTYMVCGKSCLAGDI FGEYQFDRPLSIGDRLSFIDAAGYTMVKKNWFNGLKMPSIVVKQLDGSVEVVREFVYDDY LSSLS