Protein Info for Pf6N2E2_1500 in Pseudomonas fluorescens FW300-N2E2

Annotation: LysR family transcriptional regulator lrhA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 PF00126: HTH_1" amino acids 6 to 65 (60 residues), 68.5 bits, see alignment E=4e-23 PF03466: LysR_substrate" amino acids 89 to 279 (191 residues), 94.6 bits, see alignment E=5.5e-31

Best Hits

Swiss-Prot: 47% identical to PECT_DICD3: HTH-type transcriptional regulator PecT (pecT) from Dickeya dadantii (strain 3937)

KEGG orthology group: None (inferred from 92% identity to pfs:PFLU2229)

Predicted SEED Role

"LysR family transcriptional regulator lrhA" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZVB6 at UniProt or InterPro

Protein Sequence (285 amino acids)

>Pf6N2E2_1500 LysR family transcriptional regulator lrhA (Pseudomonas fluorescens FW300-N2E2)
MSTLDLELLRTFIAVVDHHSFAEAGAQLSRTQSSVTQHMQRLEQQVGVSLFEKRGRQKQL
TEAGQQLLRHARQMLSLNDDVLSSLRESSLSGVLRIGSPHDIADTILPPILSHIARSAPR
LRLEIDVGRSPFLMDDLHRGKVDMIISTRQDPSLEGFALRTSPVWWICSAQYLHNPGEPL
PLILVDEPSIYRRYALEALERANIPWRQAYLASNLIGIKAATRAGLGVTPRSMEMLGPDM
RVLGENDGLPRLPDVTYHLWIRPNTVNPLVRRAYELIRNSQGHGN