Protein Info for Pf6N2E2_1409 in Pseudomonas fluorescens FW300-N2E2

Annotation: Excinuclease ABC subunit A paralog of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 885 PF17755: UvrA_DNA-bind" amino acids 171 to 283 (113 residues), 47.9 bits, see alignment E=3.8e-16

Best Hits

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 80% identity to pfl:PFL_3691)

Predicted SEED Role

"Excinuclease ABC subunit A paralog of unknown function" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZW43 at UniProt or InterPro

Protein Sequence (885 amino acids)

>Pf6N2E2_1409 Excinuclease ABC subunit A paralog of unknown function (Pseudomonas fluorescens FW300-N2E2)
MPPRHAPASTADLPQGTGFVRVRGAREHNLKNVDVDIPRDALVVFTGVSGSGKSSLAFST
LYAEAQRRYFESVAPYARRLIDQVGVPDVDSIEGLPPAVALQQQRGTPSARSSMGSVTTL
SSLIRMLYSRAGSYPADQPMLYAEDFSPNTPQGACQECHGLGRVYEVTEASMVPDPSLTI
RERAVAAWPMAWQGQNLRDILVTLGYDVDIPWRDLPKQQRDWILFTEQTPTVPVYAGLTP
AQTRAALKRKLEPSYQGTFSGARRYLLHTFMHSQSAQMRKRVAQYMRASPCPVCEGKRLK
RQALTVTFAGLDIAELSHLPLLELAEVLKRVLAPDYLEQAEETGDVLSHQQTRKAREQRA
ARGDNPHAGGPDARHTPNLSLEKRLAAQRIAAELLERIVTLIDLGLGYLALERSTPTLSS
GELQRLRLATQLNSQLFGVIYVLDEPSAGLHPADSEALFGALQRLKAAGNSVFVVEHDLD
TMRRADWLIDVGPDAGEQGGKVLYSGPPSGLGQVPESRTRAYLFGEEHVMARSPRTPRDW
LRLEGITRNNLDNLSAAFPLGCFTAVTGISGSGKSSLVSQALLDLVGAHLGQASPNAEPD
EQSLEDEPVQTSGGRVSAGLEAVRRLVQVDQKPIGRTPRSNLATYTGLFDHVRKLFAATA
QAQELGFDAGRFSFNVAKGRCETCEGEGFVSVELLFMPSVYAPCPTCHGARYNPQTLEVN
WQGLNISQVLQLTVNQALEVFAEQAAARRSLQVLQDIGLGYLRLGQPATELSGGEAQRIK
LATELQRKARGATLYVLDEPTNGLHPQDVDRLLVQLNRLVEDGHTVVVVEHDMRVVAQSD
WVIDIGPGAGSQGGNVVACGAPEEVAACRESRTAEFLKRALQPGR