Protein Info for Pf6N2E2_1252 in Pseudomonas fluorescens FW300-N2E2

Annotation: Catalase (EC 1.11.1.6)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 479 PF00199: Catalase" amino acids 7 to 386 (380 residues), 627.6 bits, see alignment E=8.4e-193 PF06628: Catalase-rel" amino acids 416 to 475 (60 residues), 68 bits, see alignment E=6.7e-23

Best Hits

Swiss-Prot: 74% identical to CATA_ALIF1: Catalase (katA) from Aliivibrio fischeri (strain ATCC 700601 / ES114)

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 78% identity to put:PT7_2928)

MetaCyc: 52% identical to catalase monomer (Homo sapiens)
Catalase. [EC: 1.11.1.21, 1.11.1.6]; 1.11.1.6 [EC: 1.11.1.21, 1.11.1.6]

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.21 or 1.11.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZVR3 at UniProt or InterPro

Protein Sequence (479 amino acids)

>Pf6N2E2_1252 Catalase (EC 1.11.1.6) (Pseudomonas fluorescens FW300-N2E2)
MSNHKLTTANGAPVVDNFNTQTAGPRGPALLQDVWLLEKLAHFDREVIPERRMHAKGAGA
FGTFTVTHDITHYTKADLFSSVGKQTPMFARFSTVAGERGAADAERDIRGFAMKFYTEQG
NWDLVGNNTPVFFFRDPLRFPDLNHAVKRDPRTGMRSAQNNWDFWSSLPEALHQVTIVMS
QRGIPRSYRHMHGFGSHTFSLINANNERHWVKFTFKTQQGIANLSDEQAKQLVGEDRESH
HRDLFDSIEAKDFPRWTLYIQIMTPDQAQTHPVNPFDVTKVWPHGDYPLIEVGFFELNRN
PQNVFADVEQVAFSPANIVPGIGFSPDRMLQARLFSYGDAARYRLGVNHNQIPVNQPQCP
VHSFHRDGAMRVDGNHGGTLSYVPNGQGEWLDQPEWREPPLELYGAAGHWDHRVGDDHYE
QPGNLFRQMNDQEKQALFENTARSLQSVTREVQLRHIANCNKADVGYGTGIASALAALG