Protein Info for Pf6N2E2_1122 in Pseudomonas fluorescens FW300-N2E2

Annotation: MotA/TolQ/ExbB proton channel family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 132 to 157 (26 residues), see Phobius details amino acids 174 to 195 (22 residues), see Phobius details TIGR02796: protein TolQ" amino acids 10 to 222 (213 residues), 253.7 bits, see alignment E=7.6e-80 PF01618: MotA_ExbB" amino acids 87 to 209 (123 residues), 132.6 bits, see alignment E=3.6e-43

Best Hits

Swiss-Prot: 59% identical to TOLQ_PSEAE: Tol-Pal system protein TolQ (tolQ) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03562, biopolymer transport protein TolQ (inferred from 97% identity to pba:PSEBR_a2960)

Predicted SEED Role

"MotA/TolQ/ExbB proton channel family protein" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZUC4 at UniProt or InterPro

Protein Sequence (235 amino acids)

>Pf6N2E2_1122 MotA/TolQ/ExbB proton channel family protein (Pseudomonas fluorescens FW300-N2E2)
MQATLEHMTIWGLISDASLLVKAVMLTLLLASLLSWYLIIQRSAVLQRNERQLNGFMQRF
RSSQDLLPLYREHAQVREEDAGVTPIFQAGVLAFTQLNQPSSTPEVVLEGVERALQVAIS
EQEIQLEKGLQFLATVGSVSPYIGLFGTVWGIMNAFIGLSQVQQASLSTVAPGIAEALIA
TAIGLFAAIPAVIAYNRFAARGQTLLTRYYAFGNELQARLHRKLHGAPMNLATAA