Protein Info for Pf1N1B4_828 in Pseudomonas fluorescens FW300-N1B4

Annotation: Multicopper oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 458 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF07732: Cu-oxidase_3" amino acids 54 to 161 (108 residues), 105.4 bits, see alignment E=3e-34 PF00394: Cu-oxidase" amino acids 347 to 455 (109 residues), 26.8 bits, see alignment E=7.7e-10 PF07731: Cu-oxidase_2" amino acids 350 to 457 (108 residues), 96.9 bits, see alignment E=1.3e-31

Best Hits

KEGG orthology group: None (inferred from 95% identity to pba:PSEBR_a979)

MetaCyc: 82% identical to CumA multicopper oxidase (Pseudomonas putida GB-1)

Predicted SEED Role

"Multicopper oxidase" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A166MUZ6 at UniProt or InterPro

Protein Sequence (458 amino acids)

>Pf1N1B4_828 Multicopper oxidase (Pseudomonas fluorescens FW300-N1B4)
MSFTRRQILGGLAGLVVVGVGAGGASRYWLGKMADADAGHDYELIAAPLDVELVAGHKTP
AWAFGPSAPGTELRVRQGEWLRVRFINHLPVATTIHWHGIRLPLEMDGVPYVSQLPVLPG
EYFDYKFRVPDAGSYWYHPHVNSSEELGRGLVGPLIIEEREPTGFKYEKTLSLKSWHVDE
EGAFVAFSIPREAARGGTAGGLSTINGVSQAVIDLPAGQITRVRLLNLDNTLTYRLNIPG
VEAQIYALDGNPIEPRPLGKEYWLGPGMRICLAIKAPPAGEELSLRNGPVRLGTFRSVAN
TDAPTAWPPALPANPVAEPDLANAEKLNFNFEWVGSVSVNVENGKPPSLWQINGKAWDIT
DKTCADRPIAKLEKGKSYIFELKNMTQYQHPIHLHGMSFKVIASNRHKVIPYFTDTYLLG
KNERAQVALVADNPGVWMFHCHVVDHMETGLMAAIEVA