Protein Info for Pf1N1B4_476 in Pseudomonas fluorescens FW300-N1B4

Annotation: ABC-type multidrug transport system, ATPase component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 PF00005: ABC_tran" amino acids 21 to 165 (145 residues), 119.1 bits, see alignment E=2.4e-38 PF13304: AAA_21" amino acids 129 to 194 (66 residues), 37.6 bits, see alignment E=2.6e-13

Best Hits

Swiss-Prot: 67% identical to YADG_ECOLI: Uncharacterized ABC transporter ATP-binding protein YadG (yadG) from Escherichia coli (strain K12)

KEGG orthology group: K09687, antibiotic transport system ATP-binding protein (inferred from 95% identity to pfs:PFLU1868)

Predicted SEED Role

"ABC-type multidrug transport system, ATPase component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A166MN64 at UniProt or InterPro

Protein Sequence (310 amino acids)

>Pf1N1B4_476 ABC-type multidrug transport system, ATPase component (Pseudomonas fluorescens FW300-N1B4)
MSSALSIRQLTKTYGNGFQALSGIDLDVAEGDFFALLGPNGAGKSTTIGILSTLVNKTSG
TVNIFGHDLDKNPAQLKRSIGVVPQEFNFNQFEKTFDIVVTQAGYYGIPAKIAKERAEQY
LTQLGLWDKRDVPSRSLSGGMKRRLMIARALVHEPRLLILDEPTAGVDIELRRSMWTFLT
ELNKKGITIILTTHYLEEAEQLCRNIGIIDHGTIVENTSMKQLLSQLHVETFLLDLKNTL
QVVPQLLGYPAKLIDSHTLEVQVDKAMGITALFTQLAQQNIEVLSLRNKTNRLEELFVSL
VEKNLSKVAV