Protein Info for Pf1N1B4_4470 in Pseudomonas fluorescens FW300-N1B4

Annotation: Cobalt-zinc-cadmium resistance protein CzcD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 transmembrane" amino acids 29 to 49 (21 residues), see Phobius details amino acids 59 to 78 (20 residues), see Phobius details amino acids 97 to 119 (23 residues), see Phobius details amino acids 128 to 151 (24 residues), see Phobius details amino acids 175 to 195 (21 residues), see Phobius details amino acids 201 to 221 (21 residues), see Phobius details TIGR01297: cation diffusion facilitator family transporter" amino acids 25 to 301 (277 residues), 215.5 bits, see alignment E=4.7e-68 PF01545: Cation_efflux" amino acids 32 to 232 (201 residues), 122.3 bits, see alignment E=1.2e-39

Best Hits

KEGG orthology group: None (inferred from 82% identity to pfo:Pfl01_3473)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcD" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161ZCK5 at UniProt or InterPro

Protein Sequence (305 amino acids)

>Pf1N1B4_4470 Cobalt-zinc-cadmium resistance protein CzcD (Pseudomonas fluorescens FW300-N1B4)
MTLKPQASRFTHDHLFLGPAHDENARRTLWVVALTFVMMIGEIAAGYITGSMALLADGFH
MATHAGALGIAAAAYGFARRHANNSRFSFGTGKVGDLAGFASAIVLGLVSIGIAGESIVR
LFQPTTVAFTEATVIAVVGLGVNIVSAFLLSGNHGHHGHDHHDHNHHHDNNLRSAYLHVL
ADALTSVLAIVALLAGRYLGWVWLDPVMGIVGAIVIARWAYGLMRDSAAVLLDTTDEHVA
AEIRELLESTDDVRISDLHVWQVGPQARAAIVSVVAVAGISADAIRERLAPVHELSHLTV
EYRNA