Protein Info for Pf1N1B4_3960 in Pseudomonas fluorescens FW300-N1B4

Annotation: Phosphonate uptake and metabolism regulator, LysR-family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 287 PF00126: HTH_1" amino acids 5 to 61 (57 residues), 81.9 bits, see alignment E=2.6e-27 TIGR03339: aminoethylphosphonate catabolism associated LysR family transcriptional regulator" amino acids 5 to 284 (280 residues), 352.2 bits, see alignment E=9.6e-110 PF03466: LysR_substrate" amino acids 87 to 282 (196 residues), 126.6 bits, see alignment E=8.9e-41

Best Hits

KEGG orthology group: None (inferred from 94% identity to pfo:Pfl01_3682)

Predicted SEED Role

"Phosphonate uptake and metabolism regulator, LysR-family" in subsystem Phosphonate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A162AYF7 at UniProt or InterPro

Protein Sequence (287 amino acids)

>Pf1N1B4_3960 Phosphonate uptake and metabolism regulator, LysR-family (Pseudomonas fluorescens FW300-N1B4)
MNLFQLRAFDAVAREGSFTRAAERLFISQPAVTGHIKALEEHYQITLLRRTARRVELTEE
GTKLAAITRAMFGLAEEAQVMLEANRQLLTGRLEVAADGPHMVMPMLASLRARYPGITVN
LRLGNAQETLAALLSEHADVAVLTEVEPRKGLHLQALSESRICALVPAAHPWAQQSKGVQ
LKELDQVIMVLREPSSITRRTFDEACAQARVNPRVLLELDSREAVTEAVAAELGVGVVSS
VEVSHDPRVAAVPIIGEGLVNRHMIGCMERRRDLRLIQAFFGLAPGR