Protein Info for Pf1N1B4_3437 in Pseudomonas fluorescens FW300-N1B4

Annotation: Arginine pathway regulatory protein ArgR, repressor of arg regulon

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 PF12833: HTH_18" amino acids 205 to 283 (79 residues), 84.9 bits, see alignment E=3.8e-28

Best Hits

Swiss-Prot: 80% identical to ARGR_PSEAE: HTH-type transcriptional regulator ArgR (argR) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 98% identity to pfo:Pfl01_4287)

Predicted SEED Role

"Arginine pathway regulatory protein ArgR, repressor of arg regulon" in subsystem Arginine Biosynthesis extended or Arginine Deiminase Pathway or Arginine and Ornithine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A166PAZ4 at UniProt or InterPro

Protein Sequence (301 amino acids)

>Pf1N1B4_3437 Arginine pathway regulatory protein ArgR, repressor of arg regulon (Pseudomonas fluorescens FW300-N1B4)
LRVAQRVHPDVVYELSFLQAEPPTEGAWQLPGEPWAGKLENFQKLFLLADEPPTSLAPAL
SSGLKQLVRAGCVIGGLSAGVYPLAQLGLLDGYRAAVHWRWQDDFAERFPKVIATSHLFD
WDRDRLTACGGMSVLDLLLAVLARDHGAELAGAVSEELVVERIREGGERQRIPLQNRLGS
SHPKLTQAVLLMEANIEEPLTTDEIAQHVCVSRRQLERIFKQYLNRVPSQYYLELRLNKA
RQMLMQTSKSIIQIGLSCGFSSGPHFSSAYRNFFGATPREDRNQRRSSSPFELSSVPSER
G