Protein Info for Pf1N1B4_34 in Pseudomonas fluorescens FW300-N1B4

Annotation: Xanthine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 484 transmembrane" amino acids 7 to 27 (21 residues), see Phobius details amino acids 33 to 53 (21 residues), see Phobius details amino acids 62 to 81 (20 residues), see Phobius details amino acids 88 to 109 (22 residues), see Phobius details amino acids 117 to 140 (24 residues), see Phobius details amino acids 152 to 170 (19 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 221 to 240 (20 residues), see Phobius details amino acids 303 to 322 (20 residues), see Phobius details amino acids 328 to 349 (22 residues), see Phobius details amino acids 361 to 383 (23 residues), see Phobius details amino acids 389 to 412 (24 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 2 to 410 (409 residues), 338.5 bits, see alignment E=5.7e-105 PF00860: Xan_ur_permease" amino acids 2 to 380 (379 residues), 305 bits, see alignment E=3.4e-95 TIGR03173: xanthine permease" amino acids 3 to 413 (411 residues), 511 bits, see alignment E=2.1e-157

Best Hits

Swiss-Prot: 41% identical to UACT_ECOLI: Uric acid transporter UacT (uacT) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 95% identity to pba:PSEBR_a1800)

MetaCyc: 41% identical to urate:H+ symporter (Escherichia coli K-12 substr. MG1655)
RXN-5076; TRANS-RXN0-530

Predicted SEED Role

"Xanthine permease" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161Z2X4 at UniProt or InterPro

Protein Sequence (484 amino acids)

>Pf1N1B4_34 Xanthine permease (Pseudomonas fluorescens FW300-N1B4)
MAYGLQHVLTMYGGIVAVPLIIGQAAGLSPADIGLLIAASLFAGGLATLLQTLGLPFFGC
QLPLVQGVSFSGVATMVAIVSSGGEGGFQSILGAVIAASLIGLLITPVFSRITKFFPPLV
TGIVITTIGLTLMPVAARWAMGGNSHAPDFGSMANIGLAAVTLVLVLLLSKIGSATISRL
SILLAMVIGTVIAVFLGMADFSSVTQGPMFGFPAPFHFGMPTFHFAAILSMCIVIMVTLV
ETSADILAVGEIIDTKVDSKRLGNGLRADMLSSMIAPIFGSFTQSAFAQNVGLVAVTGIK
SRFVVATGGVFLVVLGLLPFMGRVIAAVPTSVLGGAGIVLFGTVAASGIRTLSKVDYRNN
VNLIIVATSIGFGMIPIAAPNFYDHFPSWFATIFHSGISSSAIMAIVLNLAFNHLTAGNS
DQQSVFAAGTERVLRYQDLAALREGDYFSEGKLRDCDGNEIPVVEAEHGHAEPRAVHAKS
SEHV