Protein Info for Pf1N1B4_3172 in Pseudomonas fluorescens FW300-N1B4

Annotation: Deoxycytidine triphosphate deaminase (EC 3.5.4.13)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02274: deoxycytidine triphosphate deaminase
  • amino acids 4 to 187 (184 residues), 169.8 bits, E=2.4e-54
• PF00692: dUTPase
  • amino acids 80 to 184 (105 residues), 33.3 bits, E=1.8e-12

Best Hits

Swiss-Prot: 98% identical to DCD_PSEPF: dCTP deaminase (dcd) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: K01494, dCTP deaminase [EC: 3.5.4.13] (inferred from 98% identity to pfo:Pfl01_1202)

MetaCyc: 68% identical to dCTP deaminase (Rickettsia prowazekii Madrid E)
dCTP deaminase. [EC: 3.5.4.13]

Predicted SEED Role

"Deoxycytidine triphosphate deaminase (EC 3.5.4.13)" (EC 3.5.4.13)

MetaCyc Pathways

• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)

KEGG Metabolic Maps

• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.13

Sequence Analysis Tools

See A0A0F4V819 at UniProt or InterPro

Protein Sequence (188 amino acids)

>Pf1N1B4_3172 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) (Pseudomonas fluorescens FW300-N1B4)
MSIKSDKWIRRMAQEHGMIEPFVERQVRGSDDSRVISYGVSSYGYDVRCTNHFKVFTNIN
SAIVDPKNFDAGSFVDIHSDVCIIPPNSFALASTVEYFRIPRNVLTICLGKSTYARCGII
VNVTPLEPEWEGHVTLEFSNTTNLPAKIYANEGVAQMLFLESDEECEVSYKDRGGKYQGQ
RGVTLPRT