Protein Info for Pf1N1B4_3012 in Pseudomonas fluorescens FW300-N1B4

Annotation: Thiol:disulfide interchange protein DsbC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 243 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF10411: DsbC_N" amino acids 30 to 83 (54 residues), 63.6 bits, see alignment E=1.7e-21 PF13098: Thioredoxin_2" amino acids 116 to 238 (123 residues), 82.1 bits, see alignment E=6.9e-27

Best Hits

KEGG orthology group: K03981, thiol:disulfide interchange protein DsbC [EC: 5.3.4.1] (inferred from 93% identity to pfo:Pfl01_1026)

Predicted SEED Role

"Thiol:disulfide interchange protein DsbC" in subsystem Periplasmic disulfide interchange

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A166P2S2 at UniProt or InterPro

Protein Sequence (243 amino acids)

>Pf1N1B4_3012 Thiol:disulfide interchange protein DsbC (Pseudomonas fluorescens FW300-N1B4)
MRLTQIFAAAAIALVSTFAVADDTADKAIRKSLQTLELDVPVESITASPLPGLYEVKLKG
SRVLYASADGQYVVQGYLFQLKDGKPVNLTEKTERLGISKLINNIPVAETVVYPAIGETK
SHITVFTDTTCPYCHKLHAEVPALNKLGIEVRYVAFPRQGLGSAGDEQLQAVWCSKDKKA
AMDKMVDGKEIKAAKCENPVAKQFALGQSIGVNGTPAIVLADGQVIPGYQPAPQVAKLAL
GAK