Protein Info for Pf1N1B4_1962 in Pseudomonas fluorescens FW300-N1B4
Annotation: Teichoic acid export ATP-binding protein TagH (EC 3.6.3.40)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K09691, lipopolysaccharide transport system ATP-binding protein (inferred from 91% identity to pfo:Pfl01_5685)MetaCyc: 60% identical to O:8-antigen ABC transporter ATP-binding subunit (Escherichia coli O8)
TRANS-RXN-445 [EC: 7.5.2.14]
Predicted SEED Role
"Teichoic acid export ATP-binding protein TagH (EC 3.6.3.40)" in subsystem Rhamnose containing glycans or Teichoic and lipoteichoic acids biosynthesis (EC 3.6.3.40)
MetaCyc Pathways
- Escherichia coli serotype O:8 O antigen biosynthesis (2/9 steps found)
- Escherichia coli serotype O:9a O antigen biosynthesis (1/10 steps found)
- H. pylori 26695 O-antigen biosynthesis (1/21 steps found)
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.40
Use Curated BLAST to search for 3.6.3.40 or 7.5.2.14
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A162BLF2 at UniProt or InterPro
Protein Sequence (412 amino acids)
>Pf1N1B4_1962 Teichoic acid export ATP-binding protein TagH (EC 3.6.3.40) (Pseudomonas fluorescens FW300-N1B4) VTGLGKAYKQYPTRWSRLAEWLIPFSPIRHRQHWVLQDVAFEIAPGEAVGIVGVNGAGKS TLLKMITGTTQPTCGQIQLEGRVAALLELGMGFHPEFTGRQNAIMAGQLLGMQVEEIEAL MPQIEHFAEIGEAIDHPVRTYSSGMQMRLAFSVATARRPDILIVDEALSVGDAYFQHKSF ERIRSFRRAGTTLLIVSHDRSAIQSICDSAILLENGRMAMHGKPEAVMDYYNALLAEREG QTVRQEMLADGQVQTVSGTGEAGILSVRMLDERERAIDAAEVGQPVVLEVQVEVRQDIER LVLGFMIKDRLGQAMYGINTHRQDLALTDLQAGERLTYRFAFVMGLGKGNYSVALSLSRL DSHLDRNFEWRDYGLVFHVINNRHEDFVGCSWLAAKTTITRAAESIVSEHTP