Protein Info for Pf1N1B4_1802 in Pseudomonas fluorescens FW300-N1B4

Annotation: Membrane bound c-di-GMP receptor LapD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 648 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 148 to 170 (23 residues), see Phobius details PF16448: LapD_MoxY_N" amino acids 23 to 145 (123 residues), 131.4 bits, see alignment E=3.4e-42 PF00672: HAMP" amino acids 168 to 219 (52 residues), 31.4 bits, see alignment 3.8e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 234 to 393 (160 residues), 68.3 bits, see alignment E=3.2e-23 PF00990: GGDEF" amino acids 237 to 392 (156 residues), 89.2 bits, see alignment E=5.4e-29 PF00563: EAL" amino acids 417 to 644 (228 residues), 184.3 bits, see alignment E=4.9e-58

Best Hits

KEGG orthology group: None (inferred from 94% identity to pfo:Pfl01_0131)

Predicted SEED Role

"Membrane bound c-di-GMP receptor LapD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A166NE33 at UniProt or InterPro

Protein Sequence (648 amino acids)

>Pf1N1B4_1802 Membrane bound c-di-GMP receptor LapD (Pseudomonas fluorescens FW300-N1B4)
MSLFKQLLIAICLFLVVAFTGSFMVSLESSRTQYVNQLRSHAQDAATALALSLTPNIDDP
AMVELLVSSIFDSGYYASIRVVDLANDKTIVERSGIPAVTNVPDWFVKLIGLEPAGGDAL
VSRGWEQAARVEVVSHPMFALAKLWQSALGSLGWLLICGAVSAVLGALLLRRQLKPLDYM
VKQSHAIARREFLSLPELPRTPELRRVVQAMNQMVEKLKALFQEQAERSEKLRAESYQDN
LTGLANRRYFEMQLNARVSNAEQASSGYLLLLRVKDLAGLNQRLGGQRTDELLKAVGEQL
SRECAKYPETQNLVTRIRGGEFAVLAPGLVREEALQLASNLDSALASLHATGATDVASVA
SIGLAPFAHGDSPQAVIGLADQALAQAESQGEPSWACLDHSASARVGDDHHAWHTLLDQA
LDQQRFELYFQPVVASHDTQVVLHYKVLSRLLDEQDQTIPAGRFLPWLERFGWTARLDRL
MLELVLEQMAEHEESLALNLSSATLADPQALNKVFEILRQHSNLGERLTLEIGEEQLPEQ
AVLEQLTRRLRELGFSLSLQRFGGRFSMIGNLARLGLAYLKIDGSYIRAIDQESDKRLFI
EAIQRAAHSIDLPLIAERVETEGELAVIREMGLYGVQGQLFGEPKPWQ