Protein Info for Pf1N1B4_1510 in Pseudomonas fluorescens FW300-N1B4

Annotation: FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13279: 4HBT_2
  • amino acids 15 to 124 (110 residues), 41.7 bits, E=1.5e-14
• PF03061: 4HBT
  • amino acids 23 to 89 (67 residues), 33 bits, E=6.3e-12

Best Hits

KEGG orthology group: K07107, acyl-CoA thioester hydrolase [EC: 3.1.2.-] (inferred from 89% identity to pfo:Pfl01_0432)

Predicted SEED Role

"FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein"

KEGG Metabolic Maps

• Benzoate degradation via CoA ligation
• Biosynthesis of plant hormones
• Biosynthesis of unsaturated fatty acids
• Fatty acid biosynthesis
• Limonene and pinene degradation
• Ubiquinone and menaquinone biosynthesis
• alpha-Linolenic acid metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.2.-

Use Curated BLAST to search for 3.1.2.-

Sequence Analysis Tools

See A0A166N8B4 at UniProt or InterPro

Protein Sequence (141 amino acids)

>Pf1N1B4_1510 FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein (Pseudomonas fluorescens FW300-N1B4)
MRSKGVLHTDTEILVPFFDVDTMNVVWHGHYVKYLEVARCALLDTIGHNYDAMVASGYAW
PVIDLQLRYVRGAVFGQKLNVRASLVEWENSLKINYLISDLATGERLTRACSVQVAVDMS
SREMQLASPKVFTDAVERMLP