Protein Info for Pf1N1B4_1099 in Pseudomonas fluorescens FW300-N1B4

Annotation: Rod shape-determining protein MreB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 345 TIGR00904: cell shape determining protein, MreB/Mrl family" amino acids 9 to 337 (329 residues), 535.8 bits, see alignment E=1.9e-165 PF06723: MreB_Mbl" amino acids 11 to 337 (327 residues), 493.4 bits, see alignment E=6.2e-152 PF00022: Actin" amino acids 31 to 202 (172 residues), 34.3 bits, see alignment E=2.7e-12 PF00012: HSP70" amino acids 106 to 207 (102 residues), 48.3 bits, see alignment E=1.2e-16 PF14450: FtsA" amino acids 160 to 318 (159 residues), 42.4 bits, see alignment E=2.2e-14

Best Hits

Swiss-Prot: 81% identical to MREB_SALTY: Cell shape-determining protein MreB (mreB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03569, rod shape-determining protein MreB and related proteins (inferred from 99% identity to pen:PSEEN1074)

Predicted SEED Role

"Rod shape-determining protein MreB" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G1CGS4 at UniProt or InterPro

Protein Sequence (345 amino acids)

>Pf1N1B4_1099 Rod shape-determining protein MreB (Pseudomonas fluorescens FW300-N1B4)
MFKKLRGMFSSDLSIDLGTANTLIYVRERGIVLNEPSVVAIRTHGNQKSVVAVGTEAKRM
LGRTPGNIAAIRPMKDGVIADFSVCEKMLQYFINKVHENSFLQPSPRVLICVPCKSTQVE
RRAIRESALGAGAREVFLIEEPMAAAIGAGLPVEEARGSMVVDIGGGTTEIALISLNGVV
YAESVRVGGDRFDEAIITYVRRNYGSLIGESTAERIKQEIGTAYPGGEVREVDVRGRNLA
EGVPRAFTLNSNEVLEALQESLATIVQAVKSALEQSPPELASDIAERGLVLTGGGALLRD
LDKLLAQETGLPVIVAEDPLTCVARGGGRALEMMDKHTMDLLSSE