Protein Info for PFLU_RS29155 in Pseudomonas fluorescens SBW25-INTG

Annotation: mechanosensitive ion channel family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 190 transmembrane" amino acids 15 to 32 (18 residues), see Phobius details amino acids 63 to 85 (23 residues), see Phobius details amino acids 91 to 116 (26 residues), see Phobius details PF00924: MS_channel_2nd" amino acids 105 to 177 (73 residues), 32.3 bits, see alignment E=4.3e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU5924)

Predicted SEED Role

"Small-conductance mechanosensitive channel"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K414 at UniProt or InterPro

Protein Sequence (190 amino acids)

>PFLU_RS29155 mechanosensitive ion channel family protein (Pseudomonas fluorescens SBW25-INTG)
MEALQLPLPAQWIEPVWIGVQILLILLAGYLAQRFVAKGLTRLGERYPFPPQLLMPLRGG
LRWLIMGSALIFVLGRLGVSATVLWTALSGFVAVAAVAFFAMWSVLSNLLCAILIFTVGP
FRLGDIVELVDTVDKPGVKGRVVAINLLYTTLVEVAEAGTDSAMVQVPNSLFFQRSVRRW
PGTHVFPGDR