Protein Info for PFLU_RS26415 in Pseudomonas fluorescens SBW25-INTG

Annotation: histone deacetylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 PF00850: Hist_deacetyl" amino acids 19 to 282 (264 residues), 188.9 bits, see alignment E=6.8e-60

Best Hits

Swiss-Prot: 49% identical to Y1628_SYNP2: Uncharacterized protein SYNPCC7002_A1628 (SYNPCC7002_A1628) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6)

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU5376)

Predicted SEED Role

"Deacetylases, including yeast histone deacetylase and acetoin utilization protein" in subsystem Hydantoin metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K2H8 at UniProt or InterPro

Protein Sequence (306 amino acids)

>PFLU_RS26415 histone deacetylase (Pseudomonas fluorescens SBW25-INTG)
MPLPLIYHDDYSPEFPAEHRFPMDKFRLLRDHLVDSGLTEDSQLLRPQLCPAQILALAHD
TGYIERYMSGELSREDQRRLGLPWNEALARRTVRAVGGSILAAEQALEHGLACHLAGGTH
HAHYDYPAGFCIFNDLAVISHYLLASGRVNRVLIFDCDVHQGDGTARILHDTPDAITVSL
HCEKNFPARKAQSDWDIPLPMGMGDADYLKVVDDALNYLLPLYQPDLVLYDAGVDVHKDD
ALGYLKLTDAGVAARDESVMRHCLGRDIPVMGVIGGGYSKDRPALARRHGILHHSAQRVW
TSSGCH