Protein Info for PFLU_RS25495 in Pseudomonas fluorescens SBW25-INTG
Annotation: anthranilate 1,2-dioxygenase large subunit
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 74% identical to ANTDA_ACIAD: Anthranilate 1,2-dioxygenase large subunit (antA) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
KEGG orthology group: K05599, anthranilate 1,2-dioxygenase (deaminating, decarboxylating) large subunit [EC: 1.14.12.1] (inferred from 100% identity to pfs:PFLU5194)MetaCyc: 74% identical to anthranilate dioxygenase oxygenase component large subunit (Acinetobacter)
Anthranilate 1,2-dioxygenase (deaminating, decarboxylating). [EC: 1.14.12.1]
Predicted SEED Role
No annotation
MetaCyc Pathways
- anthranilate degradation I (aerobic) (1/1 steps found)
- 2-nitrobenzoate degradation II (1/3 steps found)
- superpathway of aromatic compound degradation via 3-oxoadipate (19/35 steps found)
- superpathway of aromatic compound degradation via 2-hydroxypentadienoate (13/42 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.14.12.1
Use Curated BLAST to search for 1.14.12.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See C3K202 at UniProt or InterPro
Protein Sequence (463 amino acids)
>PFLU_RS25495 anthranilate 1,2-dioxygenase large subunit (Pseudomonas fluorescens SBW25-INTG) MSGARSVEQWKTFIEGCLDFRPADEVFRIARHMFTEPELFDLEMELIFEKNWIYACHESE LAHNHDFVTMRAGRQPMIITRDGEGQLNALINACQHRGTTLTRVGKGNQSTFTCPFHAWC YKSDGRLVKVKAPGEYPEGFDKATRGLKKARIESYKGFVFISLDVKGTDSLEDFLGDATV FFDMMVAQSATGELEVLPGKSSYTYDGNWKLQNENGLDGYHVSTVHYNYVATVQHRQQVN TEHGASAGSTLDYSKLGAGDANTDDGWFAFNNGHSLLFSDMPNPSVRSGYATIMPRLIEE HGQQKAEWMMHRLRNLNIYPSLFFLDQISSQLRIIRPVAWNKTEIISQCLGVKNESDADR ENRIRQFEDFFNVSGMGTPDDLVEFREAQRGFQGRLERWSDISRGSHRWETGPTPNSEAI GIQPAMTGTEFTHEGLYVNQHRNWQQFLLKGLDNQALKLREVQ