Protein Info for PFLU_RS22865 in Pseudomonas fluorescens SBW25-INTG

Annotation: circularly permuted type 2 ATP-grasp protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 469 PF14403: CP_ATPgrasp_2" amino acids 72 to 445 (374 residues), 547.2 bits, see alignment E=1.9e-168 PF04174: CP_ATPgrasp_1" amino acids 72 to 401 (330 residues), 508.8 bits, see alignment E=5.8e-157

Best Hits

Swiss-Prot: 50% identical to Y605_MYCLE: Uncharacterized protein ML0605 (ML0605) from Mycobacterium leprae (strain TN)

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU4666)

Predicted SEED Role

"Protein containing domains DUF404, DUF407"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K0J5 at UniProt or InterPro

Protein Sequence (469 amino acids)

>PFLU_RS22865 circularly permuted type 2 ATP-grasp protein (Pseudomonas fluorescens SBW25-INTG)
MIRTYYDEMYDGAGQVRPHYREFARWLADTPAELLAQRRREADLLFHRAGITFTLYGDEQ
GTERLIPFDTIPRSIPASEWRIVERGCIQRVKALNMFLADLYHEQRIIKAGIIPAEQVLA
NEQYQLAMQGLDLHRDLYSHISGVDLVRDGDGTYYVLEDNLRTPSGVSYMLEDRKMMMRL
FPELFAAQRIAPIDHYPNLLLDTLKSSSPLDNPSVVVLTPGRFNSAFFEHAFLAREMGVE
LVEGADLFVRDDRVFMRTTDGPKAVDVIYRRLDDAFLDPLAFNPDSMLGVPGLLAAYRSG
NVVLANAIGTGVADDKSVYPFVTEMIRFYLDEEPILKNVPTFQCRKPDELSHVLANLPDL
VVKETQGSGGYGMLVGPASTAAEIEAFRARIKAKPHAYIAQPTLCLSTCPTFVENGIAPR
HIDLRPFVLSGKETRVVPGGLTRVALREGSLVVNSSQGGGTKDTWVVED