Protein Info for PFLU_RS21935 in Pseudomonas fluorescens SBW25-INTG

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1156 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 39 to 60 (22 residues), see Phobius details amino acids 66 to 87 (22 residues), see Phobius details amino acids 116 to 136 (21 residues), see Phobius details amino acids 161 to 178 (18 residues), see Phobius details amino acids 190 to 216 (27 residues), see Phobius details amino acids 242 to 261 (20 residues), see Phobius details amino acids 282 to 302 (21 residues), see Phobius details amino acids 327 to 355 (29 residues), see Phobius details amino acids 380 to 400 (21 residues), see Phobius details amino acids 411 to 433 (23 residues), see Phobius details amino acids 440 to 462 (23 residues), see Phobius details amino acids 483 to 508 (26 residues), see Phobius details PF12860: PAS_7" amino acids 642 to 756 (115 residues), 149.8 bits, see alignment E=6.6e-48 PF00512: HisKA" amino acids 797 to 863 (67 residues), 50.8 bits, see alignment 2.9e-17 PF02518: HATPase_c" amino acids 908 to 1016 (109 residues), 79 bits, see alignment E=7.2e-26 PF00072: Response_reg" amino acids 1039 to 1149 (111 residues), 45.2 bits, see alignment E=1.9e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU4471)

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K0X7 at UniProt or InterPro

Protein Sequence (1156 amino acids)

>PFLU_RS21935 sensor histidine kinase (Pseudomonas fluorescens SBW25-INTG)
MTLSSGLIAAVALAYMAIMFAIAFYGDRRRAPLPPRVRAWVYSLSLAVYCTSWTFFGAVG
QAAEQLWAFLPIYLGPVLLLVLAPWVLQKMILISKQENITSIADFIAARYGKSQSLAVVV
ALICLVGVLPYIALQLKGIVLGVNLLIGAGADTTGTRAQDTALIVSLVLALFTIVFGTRN
LDATEHHRGMVLAIAFESLVKLFAFLAVGAFVTYGLYDGFGDLFSQAILAPRLEEYWKET
VNWPSMVVQTGVAMMAIICLPRQFHVTVVENIDPQDLRLAKWVFPAYLILAALFVVPIAL
GGKMMLPGSVLPDSYVISLPMAEAHPALAVLAFIGGASAATGMVIVASIALSTMVSNDML
LPWLLRRSSAERPFEVFRHWMLSVRRVSIVIILLLAYVSYRLLGSTASLATIGQIAFAAV
TQLAPAMLGALYWKQANRRGVFAGLAAGTFLWFYTLVLPVTAKSLGWSLSLFPGLTWMHS
HPLGLSVTSLTLGTVFSLAGNFTLFVWVSMLSRTRVSEHWQAGRFIGQEISQRASARSML
SVQISDLLSLAARFVGEERAQQSFIRFAYRQGKGFNPNQNADNDWIAHTERLLAGVLGAS
STRAVVKAAIEGREMQLEDVVRIADEASEVLQFNRALLQGAIENITQGISVVDQSLKLVA
WNRRYLELFNYPDGLISVGRPIADIIRYNAERGLCGPGEAEVHVARRLHWMRQGRAHTSE
RLFPNGRVIELIGNPMPGGGFVMSFTDITAFREAEQALTEANEGLEQRVTERTHELSQLN
VALTDAKGVAESASQSKTRFLAAVSHDLMQPLNAARLFSAALSHQNDGLSSEARQLVQHL
DSSLRSAEDLISDLLDISRLENGKINPQRQPFVLNELFDTLGAEFKALAQEQGLRFRLRG
SRLRVDSDIKLLRRILQNFLTNAFRYADGPVLLGVRRRKGELCLEVWDRGPGIPQDKQKV
IFEEFKRLDSHQTRAEKGLGLGLAIADGLCRVLDHRLSVRSWPGKGSVFSVRVPLARNQA
TPLVKTPQETGLPLSGAQVLCVDNEESILIGMRSLLTRWGCEVWTATDQAQCAALLAEGV
RPQLALVDYHLDHGETGTELMGWLRAQLAEPIPGVVISADGRPEMVAEVHAAGLDYLAKP
VKPAALRALLSRHLPL