Protein Info for PFLU_RS21450 in Pseudomonas fluorescens SBW25-INTG

Annotation: M18 family aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 PF02127: Peptidase_M18" amino acids 12 to 423 (412 residues), 470.4 bits, see alignment E=5.8e-145

Best Hits

Swiss-Prot: 100% identical to APEB_PSEFS: Probable M18 family aminopeptidase 2 (apeB) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: K01267, aspartyl aminopeptidase [EC: 3.4.11.21] (inferred from 100% identity to pfs:PFLU4373)

Predicted SEED Role

"Aspartyl aminopeptidase"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K0D7 at UniProt or InterPro

Protein Sequence (429 amino acids)

>PFLU_RS21450 M18 family aminopeptidase (Pseudomonas fluorescens SBW25-INTG)
MREALNQGLIDFLKASPTPFHATAALAQRLEAAGYQRLDERETWTTEPNGRYYVTRNDSS
IIAFKLGRHSPLQGGIRLVGAHTDSPCLRVKPQPELQRQGFWQLGVEVYGGALLAPWFDR
DLSLAGRVTFRRDGKVESQLIDFKLPIAIIPNLAIHLNREANQGWAINAQTELPPILAQF
AGDERVDFRAVLTDQLAREHGLNADVVLDYELSFYDTQSAAVIGLNGDFIAGARLDNLLS
CYAGLQALLTSETDETCVLVCNDHEEVGSCSACGADGPMLEQTLRRLLPEGDEFVRTIQK
SLLVSADNAHGVHPNYAEKHDANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAQE
VPVQSFVVRSDMGCGSTIGPITASHLGVRTVDIGLPTFAMHSIRELCGSHDLAHLVKVLG
AFYASHDLP