Protein Info for PFLU_RS20590 in Pseudomonas fluorescens SBW25-INTG

Annotation: EAL domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1098 PF08447: PAS_3" amino acids 53 to 140 (88 residues), 39.7 bits, see alignment E=1.7e-13 amino acids 306 to 393 (88 residues), 37.1 bits, see alignment E=1.1e-12 TIGR00229: PAS domain S-box protein" amino acids 53 to 153 (101 residues), 24 bits, see alignment E=3.5e-09 amino acids 155 to 278 (124 residues), 47.8 bits, see alignment E=1.5e-16 amino acids 280 to 407 (128 residues), 29.2 bits, see alignment E=8.7e-11 amino acids 409 to 532 (124 residues), 67.7 bits, see alignment E=1e-22 amino acids 533 to 656 (124 residues), 69.4 bits, see alignment E=3.1e-23 PF08448: PAS_4" amino acids 56 to 148 (93 residues), 26.7 bits, see alignment E=2e-09 PF00989: PAS" amino acids 159 to 256 (98 residues), 28.5 bits, see alignment E=4.7e-10 amino acids 413 to 480 (68 residues), 23.6 bits, see alignment 1.6e-08 amino acids 538 to 647 (110 residues), 28.1 bits, see alignment E=6.1e-10 PF13188: PAS_8" amino acids 412 to 466 (55 residues), 31.5 bits, see alignment 4.2e-11 amino acids 537 to 580 (44 residues), 29.1 bits, see alignment (E = 2.5e-10) PF13426: PAS_9" amino acids 422 to 524 (103 residues), 35.7 bits, see alignment E=3.1e-12 amino acids 547 to 648 (102 residues), 32.9 bits, see alignment E=2.3e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 658 to 826 (169 residues), 156.2 bits, see alignment E=6.2e-50 PF00990: GGDEF" amino acids 661 to 822 (162 residues), 164.6 bits, see alignment E=5.7e-52 PF00563: EAL" amino acids 844 to 1081 (238 residues), 264.7 bits, see alignment E=2.4e-82

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU4198)

Predicted SEED Role

"Sensory box/GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3JZU2 at UniProt or InterPro

Protein Sequence (1098 amino acids)

>PFLU_RS20590 EAL domain-containing protein (Pseudomonas fluorescens SBW25-INTG)
MRNPVDSVPPLPRIYALDPQEAEQSWDSAPQLLAALNAARLGAWCWEIDTGRISWSRGTQ
ALFGFDPRQPLPKDLDYLDLLAPQDRGRVIRAFHAVLAGEPFEQAMHHHIQWPDGTHHWL
EINGSLAPDKAGRRRMIGVIRETTRQREREHALSHSEKRFATLFHLCPNMVLLTRQADGL
ISEANQYFEMLFGWPVADAIGRTTLDLGLWRHPEQRAQLVKATQRKGEPITMEVQFCASN
GQIHDGTLSAQKVELEGEAYLLSTFLDTTERKNAEQALKDSQERLDLALDSAQLGTWDWH
IPTGMLYGSARAAQLHGLPPEPFHESFDAFFEGMPGEERENMRNAYRTLREGPAGNYQLT
YRVPMEDGSSRYLESRARLYRDAQGAPLRMAGTLLDITDQVEREQRLTASEEKFASLFQA
SPDPICVTCLDGGAFIEINPAFTQTFGWTAAEVIDKSAEQIGLWDESSKRLERIERVIRE
QTLNNVAIMVHHKNGQSLTCVISSRLIKVGDQPCIVTTLRDITQQQRSEAALKASEEKFA
KAFHSSPDAISITERDTGRYVEVNDGFCRLTGYRAEEAIGLTLYQIGIWADENQRSALLA
ELQIKGRIHHLEMLWHNKRGDLLAVEVSVEPITLNETPCLLLTARDVSLLKNAQAQIRHL
AYHDPLTNLPNRALLMDRLSQQIALLKRHNLRGALLFLDLDHFKHINDSLGHPVGDTVLK
IVTARLEASVRMEDTVARLGGDEFVVLLSGLDGSRMEVSAQVQELADTLRELLSEPMFLD
GHRLQVTPSIGVALIPDHGSTPADLLKRADIALYRAKDSGRNTTQMFHNSMQKTASERLR
METDLRLALSRGEFSVHYQPQVDARGNKIVGAEALVRWQHPQLGAQSPAEFIKVLEDSGL
ILEVGTWILDEACAAFQQLIAEGLVDPLNFSLCVNISPRQFRQNDFVERVERSLKQHQLP
FSLLKLEITEGIVIQNLDDTISKMRRLKKLGVSFAMDDFGTGYSSLTYLKRLPVDALKID
QSFVRDATHDPNDAEIIRAIVAMARSLNLEVIAEGVETQEQLAFLQGLGCHLYQGYLHSR
PLPMLGFRERLIAGDGRA