Protein Info for PFLU_RS20365 in Pseudomonas fluorescens SBW25-INTG

Annotation: LacI family DNA-binding transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF00356: LacI" amino acids 3 to 48 (46 residues), 58 bits, see alignment 1.3e-19 PF00532: Peripla_BP_1" amino acids 60 to 307 (248 residues), 130.4 bits, see alignment E=1.9e-41 PF13407: Peripla_BP_4" amino acids 62 to 305 (244 residues), 78.4 bits, see alignment E=1.4e-25 PF13377: Peripla_BP_3" amino acids 170 to 329 (160 residues), 139.8 bits, see alignment E=1.9e-44

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 100% identity to pfs:PFLU4157)

Predicted SEED Role

"Ribose operon repressor" in subsystem D-ribose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3JZP6 at UniProt or InterPro

Protein Sequence (340 amino acids)

>PFLU_RS20365 LacI family DNA-binding transcriptional regulator (Pseudomonas fluorescens SBW25-INTG)
MATIKDVAALAGISYTTVSHVVNKTRPVSEPVRIKVEAAIKQLDYVPSAVARSLKAKTTA
TIGLLVPNSLNPYFAELARGIEDYCERNGYCVILCNSDDNAEKQRSYLRVLLEKRIDGLI
VTSVGGDDSGLAAGLSAVRTPMVIVDRALDGIDVDLVRIDHEEGAYLATRHLLELGHRDI
ACIGGPAHTRVAQMRLAGYHRALQEAGVAVAANRTQESDFTSTGGYTAAVQLLANNPPSA
IFASNDMIGFGVLRAAAERNIRVPGELSVIGFDDIQMGRYVYPALTTVGQSIVQLGETAA
ELLLRRIATPQLPIDQRIVTPSIVLRESTAPVAGTFAQYR