Protein Info for PFLU_RS19395 in Pseudomonas fluorescens SBW25-INTG

Annotation: Lrp/AsnC family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 165 transmembrane" amino acids 61 to 84 (24 residues), see Phobius details PF13404: HTH_AsnC-type" amino acids 14 to 55 (42 residues), 49 bits, see alignment E=6.4e-17 PF13412: HTH_24" amino acids 14 to 61 (48 residues), 46.5 bits, see alignment E=3.2e-16 PF01037: AsnC_trans_reg" amino acids 81 to 139 (59 residues), 43.6 bits, see alignment E=3.3e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU3971)

Predicted SEED Role

"Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system" in subsystem Branched-Chain Amino Acid Biosynthesis or Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3JYW6 at UniProt or InterPro

Protein Sequence (165 amino acids)

>PFLU_RS19395 Lrp/AsnC family transcriptional regulator (Pseudomonas fluorescens SBW25-INTG)
MDTKASGPHSAPVLDRIDEAIIEVLRHQGRITYEKLSSLVHLTPRPCLERVRKLERRGVI
RGYGAIIDVQMVSPGLSLLVLVALSNQSGRSAQKAFEACVKACPQVFECQLISGPFDYSL
RMRCRDMEHYRVLTETWLNNDELHIDKLVAHPELAVVKNTATELA