Protein Info for PFLU_RS18720 in Pseudomonas fluorescens SBW25-INTG

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details amino acids 51 to 71 (21 residues), see Phobius details amino acids 83 to 105 (23 residues), see Phobius details amino acids 111 to 131 (21 residues), see Phobius details amino acids 141 to 163 (23 residues), see Phobius details amino acids 169 to 190 (22 residues), see Phobius details amino acids 202 to 222 (21 residues), see Phobius details amino acids 228 to 246 (19 residues), see Phobius details amino acids 266 to 292 (27 residues), see Phobius details amino acids 304 to 322 (19 residues), see Phobius details amino acids 329 to 349 (21 residues), see Phobius details amino acids 360 to 379 (20 residues), see Phobius details amino acids 399 to 421 (23 residues), see Phobius details amino acids 428 to 448 (21 residues), see Phobius details PF07690: MFS_1" amino acids 21 to 410 (390 residues), 159.3 bits, see alignment E=1.2e-50 PF00083: Sugar_tr" amino acids 47 to 186 (140 residues), 25.2 bits, see alignment E=7.8e-10

Best Hits

KEGG orthology group: K08169, MFS transporter, DHA2 family, multidrug resistance protein (inferred from 100% identity to pfs:PFLU3840)

Predicted SEED Role

"Multidrug resistance protein B"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3JYA3 at UniProt or InterPro

Protein Sequence (454 amino acids)

>PFLU_RS18720 MFS transporter (Pseudomonas fluorescens SBW25-INTG)
MSSVADGLPLNKRLPAVIAISLGIGMATLDTAIVNTALPTLAEGIGTDSASVIWVVNAYQ
LAIIATVLPFASLSDVLGHRRVYLGGLLLFIVSSLFCGLAGSLLTLTAARVAQGLGAAAI
MSVNTALLRHIYPSKMLGRGLGYNSLVVGLAFTLGPTAASAILSVATWHWLYLINVPLGL
LALALGLRSLPTLPMTGHAFDRLAALLCAGLFALLVLGLGTAVHGAQGALTLGLITVALV
CGALLLRRQAGHPAPMLALDLFKRPVFALSSLTAICAFSAQGLAFVSLPFLLQAVLGHSQ
VETGFLMTPWPAVVAVMALVAGRLADRVSLGLLCGIGLLMLSVGMAALASLDSGASAFDI
GWRMALCGAGFGFFQSPNLKALMTSAPLARSGGASGIVAISRLLGQTLGASLVALCFHLS
LASGPHSALWLGCGFAAVGAVASGLRLLPYGKKP