Protein Info for PFLU_RS18295 in Pseudomonas fluorescens SBW25-INTG

Annotation: helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 PF13560: HTH_31" amino acids 30 to 84 (55 residues), 38.5 bits, see alignment E=2.3e-13 PF01381: HTH_3" amino acids 32 to 84 (53 residues), 45.5 bits, see alignment E=1.2e-15 PF07883: Cupin_2" amino acids 147 to 201 (55 residues), 45.1 bits, see alignment E=1.3e-15 PF02311: AraC_binding" amino acids 154 to 200 (47 residues), 27 bits, see alignment 6.9e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU3753)

Predicted SEED Role

"HigA protein (antitoxin to HigB)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3JY10 at UniProt or InterPro

Protein Sequence (208 amino acids)

>PFLU_RS18295 helix-turn-helix domain-containing protein (Pseudomonas fluorescens SBW25-INTG)
MNFLHVLPEPPEPLPKPSPDDDVISLCVAHNLQRLRSKRHLSLDGLARVCGVSRAMLAQI
ESGRSVPSIKVLCKIAKGLKVSVAAFLEDRAFEGVEVLPARQSKRLVSADGGFISRALFP
YDTARQSEFYEIRLRALGEEISEGHGPGIQENLVVAQGVLEVSVNDERYLLSTGDSILFY
ADQPHRYRNPADSEAVAFLVITYPERLD