Protein Info for PFLU_RS17140 in Pseudomonas fluorescens SBW25-INTG

Annotation: AAA family ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1212 transmembrane" amino acids 1125 to 1142 (18 residues), see Phobius details PF13555: AAA_29" amino acids 27 to 56 (30 residues), 27 bits, see alignment (E = 4.6e-10) PF13558: SbcC_Walker_B" amino acids 1114 to 1171 (58 residues), 37.1 bits, see alignment 4.5e-13

Best Hits

KEGG orthology group: K03546, exonuclease SbcC (inferred from 100% identity to pfs:PFLU3513)

Predicted SEED Role

"Exonuclease SbcC" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3KDI2 at UniProt or InterPro

Protein Sequence (1212 amino acids)

>PFLU_RS17140 AAA family ATPase (Pseudomonas fluorescens SBW25-INTG)
MKILAIRLKNLASLAGPFEIDFTAEPLASAGLFAITGPTGAGKSTLLDALCLALFGAVPR
LGDTGQAKMPDADSDISIGDPRTLLRRGTGGGYAEVDFVGVSGRRYRARWEANRARDKAS
GKLQNSRQSLIDLDSDQLLASQKTEYKTQLELSLGLNFEQFTRAVLLAQSEFSAFLKAND
NERSELLEKLTDTALYTQLGRRAFDKAKDARDAHKQLQDQATGVVPLAAEARAELDQQFD
AAQQQLKAQQAQLKQLELQHTWLKELREWQERQLAATEQLQRAQAEWDTQAPQRQDLSRL
EQLAPQRHQFARQAELNTVLAPLAEQIQSHSQQQAELHTRQEQAQQQQASAQTALAAALK
HQGDAAPLLRQAFEEQSTLAHLTKALAKRTEDKQQHETACAEGQSQLNGLLEKQRQVAER
LQRLATELDRSAALAPLSDAWSAYRDRLQQLMLIGNRLNKGQAELPQLEQRATAAVEQFT
QQREALDLLYQEAGAEPHAVAEQIQLLASLLQDNRKQQRAFEDLTRLWDSQQQLDQQASA
LTQKLTDAQQQREQLNQTGLHTKAELAIAEQTLTVTKQLLERQRLARSASVEELRAQLQD
DQPCPVCGSHEHPYHQPEALLQSLGRHDENEEATAQKAVDTLKEKLTELRGEVGGLIAQQ
KEYLQQQEQLATHQQALKPSLEAHPLAATLFNQDAAKRSAWLDQQLSQLTQSITQDEQRQ
AALLNLQQNAGRLQQQVQAAQEASQQARQLLVDQQRELASDRERLEQELNAFTSLLPADT
LEGLRAEPAATFMQLDQQVSQRLEQLGHQRDELAEQQERQQAIEKEQTHQQHRQQQLEAL
VQQVTELATQQQAAQQTLSALLGEHSSAEQWQQHVDQAVTLSRQNETDANQQLQAIHNAR
LQLTADLKALHERQQALQAEQHSLDTRISEWRALHPELDDEGLNRLLAYDDAQVSQLRQQ
LQHSEKAVEQAKVLLQEREQRLAEHQALHNGNLDTEALDSALASLNQQLAEGEKQCAELR
ARQSEDQRRQDANQAFAEQIAKAYDEWQRWARLNALIGSATGDTFRKIAQAYNLDLLVHH
ANVQLRQLVRRYRLKRGGSMLGLLVMDTEMGDELRSVHSLSGGETFLVSLALALGLASMA
SSTLKIESLFIDEGFGSLDPESLQLAMDALDGLQAQGRKVAVISHVQEMHERIPVQIQVK
RQGNGLSTLEVK