Protein Info for PFLU_RS15785 in Pseudomonas fluorescens SBW25-INTG

Annotation: type II secretion system protein GspH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 153 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details PF07963: N_methyl" amino acids 5 to 28 (24 residues), 37 bits, see alignment 1.6e-13 TIGR01708: type II secretion system protein H" amino acids 5 to 149 (145 residues), 110.7 bits, see alignment E=5.5e-36 TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 6 to 28 (23 residues), 35.2 bits, see alignment 7e-13 PF12019: GspH" amino acids 44 to 141 (98 residues), 28.8 bits, see alignment E=1.5e-10

Best Hits

KEGG orthology group: K02457, general secretion pathway protein H (inferred from 100% identity to pfs:PFLU3239)

Predicted SEED Role

"General secretion pathway protein H"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3KCW7 at UniProt or InterPro

Protein Sequence (153 amino acids)

>PFLU_RS15785 type II secretion system protein GspH (Pseudomonas fluorescens SBW25-INTG)
MTAARQHGFTLIELMVVLIIIGIASAAVGLSIKPDPLHLLRQDANRLVQLLQVAQAEALA
DGRPITWLADTKGFHFSRRNEHATGFDQFNSDPQLRPRAWDTPAVQVRVIPKQRVVLNAE
WFDTPLQLQLSDGQNSLSVRRTAAGQFRVEATP