Protein Info for PFLU_RS15410 in Pseudomonas fluorescens SBW25-INTG

Annotation: zinc-dependent alcohol dehydrogenase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF08240: ADH_N" amino acids 28 to 90 (63 residues), 43.7 bits, see alignment E=3.3e-15 PF00107: ADH_zinc_N" amino acids 162 to 272 (111 residues), 66.3 bits, see alignment E=4e-22 PF13602: ADH_zinc_N_2" amino acids 189 to 325 (137 residues), 43.7 bits, see alignment E=8.1e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU3160)

Predicted SEED Role

"Quinone oxidoreductase (EC 1.6.5.5)" in subsystem ZZ gjo need homes (EC 1.6.5.5)

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.5

Use Curated BLAST to search for 1.6.5.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3KBQ2 at UniProt or InterPro

Protein Sequence (340 amino acids)

>PFLU_RS15410 zinc-dependent alcohol dehydrogenase family protein (Pseudomonas fluorescens SBW25-INTG)
MSRTIRFHKFGPAEVLKCEEHAAAQPAPGEVQVRVEAIGISWYDILWRQNLASSHARLPS
GLGHEMAGVVVALGDGVDDLAVGDKVASFPAESPNDYPVYGEQIVLPRSALTRYPDVLSP
IEASVHYTPLLIAYFAYVDLARVKPGQFALVTDASHCAGPSFVQLGKALGVRVIAATKDS
AEREYLLSLGAEKVIVTEEQDLLMQINKFTDNRGVDVVFDGLGGPQMSLLGDVLAPRGSL
VLYGLQGGNQTPFPACAAFQKNIQFFVHCIGNFTGKPELGIIQDQVALQRALRDINQLTA
DRVLVPLKTTVFPFNQFVEAHRYMDECPCRERVALQVEAV