Protein Info for PFLU_RS12095 in Pseudomonas fluorescens SBW25-INTG

Annotation: nucleoside-specific channel-forming protein Tsx

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF03502: Channel_Tsx" amino acids 58 to 315 (258 residues), 236.9 bits, see alignment E=1.5e-74

Best Hits

Swiss-Prot: 55% identical to TSX_SALTI: Nucleoside-specific channel-forming protein Tsx (tsx) from Salmonella typhi

KEGG orthology group: K05517, nucleoside-specific channel-forming protein (inferred from 100% identity to pfs:PFLU2471)

MetaCyc: 52% identical to nucleoside-specific channel-forming protein Tsx (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-468

Predicted SEED Role

"Nucleoside-specific channel-forming protein Tsx precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K8P1 at UniProt or InterPro

Protein Sequence (315 amino acids)

>PFLU_RS12095 nucleoside-specific channel-forming protein Tsx (Pseudomonas fluorescens SBW25-INTG)
MHFTSRRPTSFGVSLLLAAVTGVLSAPILAQEKPVDDSAQGETLSPEANPAKKGVYLSDW
FNQDLTLIGSKDISFGPKPQDDIYLEYEYFGRKGPFELYGYIDVPKILTIGNSNDKGVWD
HGSPVFMEHEPRISIDYLAGRSLAIGPFKEWYVAFDWIYDHGSNKENRANTLYSGLGTDI
DTHSRVNLSANFYGRYQWENYGASNEYSWDGYRAQMKYIVPIGKFDNGASLTYIGFTNYD
FGSDLHKDNPARTANSVVATNVLLYSFTHLRFTLVGRYFHNGGNWEDGSELNFGEGNFRA
RSDGWGYYAGVGYQF