Protein Info for PFLU_RS11765 in Pseudomonas fluorescens SBW25-INTG

Annotation: TetR/AcrR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 209 PF00440: TetR_N" amino acids 12 to 53 (42 residues), 37.8 bits, see alignment 1.3e-13 PF16925: TetR_C_13" amino acids 104 to 184 (81 residues), 27.8 bits, see alignment E=2.1e-10

Best Hits

Swiss-Prot: 38% identical to NEMR_ECOL6: HTH-type transcriptional repressor NemR (nemR) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU2397)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K993 at UniProt or InterPro

Protein Sequence (209 amino acids)

>PFLU_RS11765 TetR/AcrR family transcriptional regulator (Pseudomonas fluorescens SBW25-INTG)
MSRETKSARQAILETAQPIVGAKGFSAVGLNEILHAADVPKGSFYHYFNSKDAFGVVLLD
TYFDNYLNAMQQLFNQPGLSQHAKLMRYWQSWINNQTGCTDAGKCLAVKLGAEVSDLSEP
MRLALQRGTARTIGLLSEALQQGVEDGSVTITQHPESLARRLYALWLGTSVMSKITRTAA
PFDEALGLTRQLLGQPEETDTHPYRGTGK