Protein Info for PFLU_RS11400 in Pseudomonas fluorescens SBW25-INTG

Annotation: helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 199 PF13560: HTH_31" amino acids 15 to 69 (55 residues), 36.8 bits, see alignment E=8.1e-13 PF01381: HTH_3" amino acids 19 to 73 (55 residues), 46.5 bits, see alignment E=6e-16 PF13443: HTH_26" amino acids 20 to 73 (54 residues), 28.7 bits, see alignment E=2.7e-10 PF07883: Cupin_2" amino acids 130 to 191 (62 residues), 41.3 bits, see alignment E=2.1e-14

Best Hits

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a2211)

Predicted SEED Role

"Transcriptional regulator, MerR family" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K8G1 at UniProt or InterPro

Protein Sequence (199 amino acids)

>PFLU_RS11400 helix-turn-helix domain-containing protein (Pseudomonas fluorescens SBW25-INTG)
MSTETAPRLKLEQYLGLQIKRQRQAQDLKLSDVAKIADISQGMLSKIENAQVSTSLDTLS
RLCDVLGLPLSKLFSEYDQQDGSALLVKADQGMEVVRRGTEKGHTYHLLNHTRGPKKSFE
AYMVSMDDASEEFPTFAHPGTEFLHLLEGELIYRHGNQLYRMEAGDSLTFEGEIPHGPEE
LVRVPIRLLSIMNYGNDKE