Protein Info for PFLU_RS07250 in Pseudomonas fluorescens SBW25-INTG

Annotation: M48 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01435: Peptidase_M48" amino acids 62 to 251 (190 residues), 120.1 bits, see alignment E=2.1e-38 PF14559: TPR_19" amino acids 284 to 339 (56 residues), 34 bits, see alignment 5.9e-12 amino acids 345 to 404 (60 residues), 34.5 bits, see alignment E=4.3e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU1472)

Predicted SEED Role

"Exported zinc metalloprotease YfgC precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3KEC9 at UniProt or InterPro

Protein Sequence (477 amino acids)

>PFLU_RS07250 M48 family metallopeptidase (Pseudomonas fluorescens SBW25-INTG)
MTFLRPTLLTLACLLASPGFADDLPSLGDASSAIVSPQQEYQLGRAWLAYLRGQVSQLND
PQLKDYVETSVYKLVETSQVNDRRLEFILINSPQLNAFAAPGGIVGVNGGLFLNAQTEGE
YASVLAHELAHLSQRHFARGVEAQQRMQIPMMAALLGGIIAAAAGAGDAGIAAIAGTQAA
AIQEQRRFSRQNEQEADRIGILNLEKAGYDPRSMPTMFERLMRQYRFDAKPPEFLLTHPV
TESRIADTRNRAEQSKPGGKEDSLRYQLIRARVQLQYEDTSGLAAKRFQAQLDENPKNDV
ARYGLAIAQIKGSQFKQARENLAALLAKAPNDITYNLAQIQLDIDNSRLPDAQQRTDRML
TQYPGNYPLNQVRVDLLLKQNRTADAEKALDSLLKSRPDDPDVWYQVAETRGLSGNIIGL
HQARAEYFALVGDFQQAIQQLDFAKRRAGNNFPLSSRIDARQRELIEQERLVKGMMS