Protein Info for PFLU_RS05080 in Pseudomonas fluorescens SBW25-INTG

Annotation: IclR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 259 PF09339: HTH_IclR" amino acids 14 to 64 (51 residues), 48.5 bits, see alignment 6.2e-17 PF01614: IclR" amino acids 130 to 253 (124 residues), 58.3 bits, see alignment E=7.7e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU1024)

Predicted SEED Role

"Transcriptional regulator, IclR family" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K5C9 at UniProt or InterPro

Protein Sequence (259 amino acids)

>PFLU_RS05080 IclR family transcriptional regulator (Pseudomonas fluorescens SBW25-INTG)
MEKPRDTGKQKVRSAEVGTDILKALAELSPATSLSRLAEHVQMPASKVHRYLQALIASGF
AEQNTATNHYGLGREALRVGLAALGSMDVLKVGAMPLAELRDELNETCFLAVWGNQGATV
VQIEPAVRAVTVVTQLGSVLPLLSSSTGLVFSAFLPSRETVELREREIQAGTAHALADDQ
AYATACEQIRRRGLHFVHGLLMPGVDALSAPVFNAVGQVAAVMTVVGPTSLFHADEDGPA
AQRLLAATQAVSWRMGYQP