Protein Info for PFLU_RS01880 in Pseudomonas fluorescens SBW25-INTG

Annotation: twin-arginine translocase subunit TatC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 transmembrane" amino acids 25 to 47 (23 residues), see Phobius details amino acids 80 to 101 (22 residues), see Phobius details amino acids 113 to 139 (27 residues), see Phobius details amino acids 162 to 188 (27 residues), see Phobius details amino acids 198 to 215 (18 residues), see Phobius details amino acids 222 to 241 (20 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 14 to 231 (218 residues), 250.4 bits, see alignment E=8.5e-79 PF00902: TatC" amino acids 16 to 226 (211 residues), 240.5 bits, see alignment E=8.2e-76

Best Hits

Swiss-Prot: 72% identical to TATC_AZOCH: Sec-independent protein translocase protein TatC (tatC) from Azotobacter chroococcum mcd 1

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 100% identity to pfs:PFLU0382)

MetaCyc: 60% identical to twin arginine protein translocation system - TatC protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K8T7 at UniProt or InterPro

Protein Sequence (263 amino acids)

>PFLU_RS01880 twin-arginine translocase subunit TatC (Pseudomonas fluorescens SBW25-INTG)
MSADKPENDQHMPLVSHLTELRTRLLRCVAAIFIIFAGLFAFTQQIYTFVSTPLRQYLPA
GATMIATDVSSPFLTPLKLTMMVSLFLAIPVILHQIWGFIAPGLYKHEKRIAVPLLVSSI
LLFYTGMAFAYFLVFPLIFKFFAAATPAGVEMMTDITSYLDFVMTLFFAFGVAFEIPVAV
VLLVWIGVVNVQYLKKIRPYVIIGCFVVGMILTPPDIFSQTLLAVPMWMLFEIGILFSSL
ITKRGEHPDDQTADDDQPPATQP