Protein Info for MPMX20_04762 in Enterobacter sp. TBS_079

Annotation: Virulence regulon transcriptional activator VirB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 323 TIGR00180: ParB/RepB/Spo0J family partition protein" amino acids 53 to 213 (161 residues), 90.3 bits, see alignment E=6.4e-30 PF08775: ParB" amino acids 193 to 318 (126 residues), 138.2 bits, see alignment E=2.1e-44

Best Hits

Swiss-Prot: 52% identical to PARB_ECOLX: Plasmid Partition par B protein (parB) from Escherichia coli

KEGG orthology group: K03497, chromosome partitioning protein, ParB family (inferred from 65% identity to kpe:KPK_B0097)

Predicted SEED Role

"Chromosome (plasmid) partitioning protein ParB" in subsystem Bacterial Cytoskeleton or Plasmid replication or Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (323 amino acids)

>MPMX20_04762 Virulence regulon transcriptional activator VirB (Enterobacter sp. TBS_079)
MSGHRKTIGRNFNSQATVESSSSGLQVQYFTLKTGRKVKFTLITVPAAEVAEKTYVRQET
NGRDQSALTKDSLKDITRTIRFQQFFACIGVLDGEKIEILDGSRRRASAIEVHTALNVMV
TSDKLTAEEARQLAKDIQTAKEHNIREIGLRLLSLKESGLNQKEIAEQEGLSQAKVTRAI
QAATVPQELISLFPVQYELSFSDYKNLSELNDRLKEKSIEYFQLIESISAQLDVLAADDR
LQEDEKKAAILKLIAKGAASLIAEPPKEKTTVSSLWEFADKDKFARKRVKGRSFTYEFNR
LPKNLQHDIDSAIQDVLKRHSGE