Protein Info for MPMX20_04528 in Enterobacter sp. TBS_079

Annotation: Catalase-peroxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00198: catalase/peroxidase HPI
  • amino acids 18 to 725 (708 residues), 1311.2 bits, E=0
• PF00141: peroxidase
  • amino acids 92 to 396 (305 residues), 140.5 bits, E=4e-45
  • amino acids 403 to 699 (297 residues), 91.7 bits, E=3.3e-30

Best Hits

Swiss-Prot: 92% identical to KATG_ENT38: Catalase-peroxidase (katG) from Enterobacter sp. (strain 638)

KEGG orthology group: K03782, catalase/peroxidase [EC: 1.11.1.6 1.11.1.7] (inferred from 96% identity to enc:ECL_05036)

MetaCyc: 87% identical to catalase/hydroperoxidase HPI (Escherichia coli K-12 substr. MG1655)
Catalase. [EC: 1.11.1.21, 1.11.1.6]; 1.11.1.21 [EC: 1.11.1.21, 1.11.1.6]

Predicted SEED Role

"Catalase (EC 1.11.1.6) / Peroxidase (EC 1.11.1.7)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) or Auxin degradation (EC 1.11.1.6, EC 1.11.1.7)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethanol degradation IV (3/3 steps found)
• superoxide radicals degradation (2/2 steps found)
• betanidin degradation (1/1 steps found)
• baicalein degradation (hydrogen peroxide detoxification) (1/2 steps found)
• methanol oxidation to formaldehyde IV (1/2 steps found)
• luteolin triglucuronide degradation (1/4 steps found)
• xanthommatin biosynthesis (1/4 steps found)
• sesamin biosynthesis (1/8 steps found)
• justicidin B biosynthesis (1/10 steps found)
• matairesinol biosynthesis (1/10 steps found)

KEGG Metabolic Maps

• Biosynthesis of phenylpropanoids
• Methane metabolism
• Phenylalanine metabolism
• Phenylpropanoid biosynthesis
• Tryptophan metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.21 or 1.11.1.6 or 1.11.1.7

Protein Sequence (726 amino acids)

>MPMX20_04528 Catalase-peroxidase (Enterobacter sp. TBS_079)
MSTSDDSNNAASIGKCPFHQGSVDHSAGAGTGSRDWWPKQLRVDLLNQHSNRSNPLGEDF
DYRKEFSKLDYSALKGDLKALLTDSQPWWPADWGSYAGLFIRMAWHGAGTYRSVDGRGGA
GRGQQRFAPLNAWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFG
FGAGREDVWEPDMDVNWGDEKAWLTHRDPEALAKRPLAATEMGLIYVNPEGPNASGEPLS
AAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGEATHVGADPEAAPIEAQGLGWTST
HGTGVGADAITSGLEVIWSQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPDIMP
DPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKA
RYIGPEVPKEDLIWQDPLPQAVFNPTKEDIESLKAEIIASGLSVSDLVSVAWASASTFRG
GDKRGGANGARLALAPQRDWEVNAAAVRALPALEAIQRTTNKASLADIIVLAGVVGVEQA
AKEAGVYVNVPFTPGRVDARQDQTDIEMFNLLEPIADGFRNYRAQVDASTTESLLIDKAQ
QLTLTAPELTVLIGGLRVLGANFDGSQNGVFTHREGVLSNDFFVNLLDMNTQWKATDESN
ELFAGSDRASGEVKYTATRADLVFGSNAVLRALAEVYASSDAHEKFVRDFVAAWAKVMDL
DRFDLQ