Protein Info for MPMX20_04424 in Enterobacter sp. TBS_079
Annotation: Endoglucanase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 61% identical to GUN_CELUD: Endoglucanase from Cellulomonas uda
KEGG orthology group: K01179, endoglucanase [EC: 3.2.1.4] (inferred from 79% identity to ent:Ent638_3936)Predicted SEED Role
"Endoglucanase precursor (EC 3.2.1.4)" (EC 3.2.1.4)
MetaCyc Pathways
- cellulose degradation II (fungi) (2/3 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.4
Use Curated BLAST to search for 3.2.1.4
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (331 amino acids)
>MPMX20_04424 Endoglucanase (Enterobacter sp. TBS_079) MRKPACAALAVMMSLLFSPLSQAGQAWESYKARFFTPEGRIVDTGNGNVSHTEGQGFAML MAVANDDKATFDKLWKWTDSTLNNKENGLFYWRYNPAESNPIADKNNAADGDVLIAWALL KADTRWHDKQYSAASDAITKALISHTVTRYAGYRVMLPGVQGFTLDGEIVLNPSYFVFPA WQAFASRSHSPVWGKLIQDGHRLLAKMGSGKVRLPTDWVSLGSTGTLSPAKAWPPRMSYD AIRIPLYLAWSDKKSPLLTPWRAWFGQFPREQTPAWVNVTTNEYAPYMMEGGLLAVRDLT MGQPSGEPEITAKDDYYSASLKMLVWLAEQP