Protein Info for MPMX20_04380 in Enterobacter sp. TBS_079

Annotation: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 transmembrane" amino acids 54 to 69 (16 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details PF01041: DegT_DnrJ_EryC1" amino acids 12 to 374 (363 residues), 444.8 bits, see alignment E=5.4e-137 PF01053: Cys_Met_Meta_PP" amino acids 33 to 166 (134 residues), 33.8 bits, see alignment E=2.9e-12 PF01212: Beta_elim_lyase" amino acids 34 to 275 (242 residues), 31.8 bits, see alignment E=2e-11 PF00155: Aminotran_1_2" amino acids 36 to 166 (131 residues), 36.3 bits, see alignment E=7.8e-13

Best Hits

Swiss-Prot: 86% identical to ARNB_KLEP3: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (arnB) from Klebsiella pneumoniae (strain 342)

KEGG orthology group: K07806, UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase [EC: 2.6.1.87] (inferred from 94% identity to enc:ECL_04863)

MetaCyc: 80% identical to UDP-4-amino-4-deoxy-L-arabinose aminotransferase (Escherichia coli K-12 substr. MG1655)
RXN0-1863 [EC: 2.6.1.87, 2.6.1.92]

Predicted SEED Role

"UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (EC 2.6.1.-)" in subsystem Lipid A-Ara4N pathway ( Polymyxin resistance ) (EC 2.6.1.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.-

Use Curated BLAST to search for 2.6.1.- or 2.6.1.87 or 2.6.1.92

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (380 amino acids)

>MPMX20_04380 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (Enterobacter sp. TBS_079)
MMSDFLPFSRPSMGSEELAALQEVLTSGWITTGPKNQALEEAFCQLTGNQHAIAVSSATA
GMHVTLMALGIGPGDEVITPSLTWVSTLNMIVLLGATPVMIDVDRDTLMITPDAVDAAIT
PRTKAIVPVHYAGAPCDIDAIRAIGERHGIPIIEDAAHAAGTYYHSRHVGWQGTAIFSFH
AIKNMTCAEGGLVVTDDAQLAQRIRSLKFHGLGVDAYDRQTHGRAPQAEVITPGFKYNLA
DINAALALVQLGKLKEANARRHDIAERYLRELADTPFQPLRIPSWPHVHAWHLFIIRVDE
ARCGISRDNLMAALKEKGIGTGLHFRAAHTQKYYRERFPDVSLPNSEWNSARICSLPLFP
DMTHDDTTRVITALHQLAGN